Ticker: CNTA CUSIP: 152309100 Class: ADR
Note: Option positions (PUT/CALL) are excluded.
| Institution | Shares | Value ($000) |
|---|---|---|
| BRAIDWELL LP | 2,188,320 | $54,730 |
| Sofinnova Investments, Inc. | 1,104,274 | $27,618 |
| Deep Track Capital, LP | 2,000,000 | $50,020 |
| MAVERICK CAPITAL LTD | 1,643,724 | $41,110 |
| Persistent Asset Partners Ltd | 43,266 | $1,082 |
| DIADEMA PARTNERS LP | 90,000 | $2,251 |
| SummitTX Capital, L.P. | 332,708 | $8,321 |
| Rhenman & Partners Asset Management AB | 100,000 | $2,501 |
| Burkehill Global Management, LP | 150,000 | $3,752 |
| BAKER BROS. ADVISORS LP | 670,751 | $16,775 |
| SEVEN GRAND MANAGERS, LLC | 50,000 | $1,251 |
| OXFORD ASSET MANAGEMENT LLP | 11,166 | $279 |
| XTX Topco Ltd | 79,077 | $1,978 |
| Walleye Capital LLC | 441,160 | $11,033 |
| Aigen Investment Management, LP | 12,569 | $314 |
| Voleon Capital Management LP | 79,074 | $1,978 |
| Aquatic Capital Management LLC | 69,755 | $1,745 |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 348,279 | $8,710 |
| Atom Investors LP | 18,347 | $459 |
| Knott David M Jr | 4,000 | $100 |
| Institution | Prev Shares | Curr Shares | Change |
|---|---|---|---|
| EcoR1 Capital, LLC | 550,000 | 3,115,000 | +2,565,000 (+466.4%) |
| STEMPOINT CAPITAL LP | 655,385 | 1,154,114 | +498,729 (+76.1%) |
| Avoro Capital Advisors LLC | 10,808,080 | 14,555,555 | +3,747,475 (+34.7%) |
| TCG Crossover Management, LLC | 3,136,480 | 4,286,480 | +1,150,000 (+36.7%) |
| Foresite Capital Management VI LLC | 1,314,019 | 1,364,019 | +50,000 (+3.8%) |
| Siren, L.L.C. | 3,227,517 | 4,027,517 | +800,000 (+24.8%) |
| SILVERARC CAPITAL MANAGEMENT, LLC | 141,238 | 458,203 | +316,965 (+224.4%) |
| Rock Springs Capital Management LP | 69,240 | 324,015 | +254,775 (+368.0%) |
| FARALLON CAPITAL MANAGEMENT LLC | 4,331,318 | 5,377,068 | +1,045,750 (+24.1%) |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 10,035,000 | 11,281,741 | +1,246,741 (+12.4%) |
| Jain Global LLC | 241,975 | 915,803 | +673,828 (+278.5%) |
| Woodline Partners LP | 107,671 | 578,251 | +470,580 (+437.1%) |
| ARMISTICE CAPITAL, LLC | 378,000 | 500,000 | +122,000 (+32.3%) |
| FEDERATED HERMES, INC. | 1,749,650 | 2,342,139 | +592,489 (+33.9%) |
| ROYCE & ASSOCIATES LP | 247,387 | 362,873 | +115,486 (+46.7%) |
| Trexquant Investment LP | 62,310 | 146,523 | +84,213 (+135.2%) |
| MILLENNIUM MANAGEMENT LLC | 902,268 | 1,870,671 | +968,403 (+107.3%) |
| D. E. Shaw & Co., Inc. | 64,389 | 831,636 | +767,247 (+1191.6%) |
| FMR LLC | 6,277,243 | 8,961,939 | +2,684,696 (+42.8%) |
| Candriam S.C.A. | 343,207 | 395,623 | +52,416 (+15.3%) |
| Institution | Prev Shares | Curr Shares | Change |
|---|---|---|---|
| First Light Asset Management, LLC | 3,635,816 | 2,278,940 | -1,356,876 (-37.3%) |
| Saturn V Capital Management LP | 734,539 | 282,692 | -451,847 (-61.5%) |
| GENERAL ATLANTIC, L.P. | 9,681,818 | 6,117,715 | -3,564,103 (-36.8%) |
| Commodore Capital LP | 2,850,000 | 1,000,000 | -1,850,000 (-64.9%) |
| Cormorant Asset Management, LP | 1,925,000 | 1,325,000 | -600,000 (-31.2%) |
| 5AM Venture Management, LLC | 680,945 | 580,945 | -100,000 (-14.7%) |
| Affinity Asset Advisors, LLC | 1,107,162 | 600,552 | -506,610 (-45.8%) |
| Octagon Capital Advisors LP | 830,000 | 750,000 | -80,000 (-9.6%) |
| Logos Global Management LP | 525,000 | 200,000 | -325,000 (-61.9%) |
| PERCEPTIVE ADVISORS LLC | 3,100,902 | 2,917,634 | -183,268 (-5.9%) |
| PFM Health Sciences, LP | 666,196 | 591,601 | -74,595 (-11.2%) |
| Blue Owl Capital Holdings LP | 169,450 | 139,450 | -30,000 (-17.7%) |
| RTW INVESTMENTS, LP | 2,291,747 | 1,790,837 | -500,910 (-21.9%) |
| PLATINUM INVESTMENT MANAGEMENT LTD | 186,399 | 155,101 | -31,298 (-16.8%) |
| Nantahala Capital Management, LLC | 404,803 | 254,803 | -150,000 (-37.1%) |
| HighVista Strategies LLC | 63,301 | 44,490 | -18,811 (-29.7%) |
| ADAR1 Capital Management, LLC | 53,666 | 38,566 | -15,100 (-28.1%) |
| JANUS HENDERSON GROUP PLC | 5,408,199 | 4,093,608 | -1,314,591 (-24.3%) |
| Cinctive Capital Management LP | 92,628 | 72,831 | -19,797 (-21.4%) |
| BALYASNY ASSET MANAGEMENT L.P. | 805,611 | 468,815 | -336,796 (-41.8%) |
| Institution | Prev Shares | Prev Value ($000) |
|---|---|---|
| Tanager Wealth Management LLP | 598,044 | $14,503 |
| Exome Asset Management LLC | 88,024 | $2,135 |
| Windmill Hill Asset Management Ltd | 163,768 | $3,971 |
| Artia Global Partners LP | 133,291 | $3,232 |
| TANG CAPITAL MANAGEMENT LLC | 200,000 | $4,850 |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 515,979 | $12,512 |
| Point72 Asset Management, L.P. | 1,072,665 | $26,012 |
| PRELUDE CAPITAL MANAGEMENT, LLC | 26,656 | $646 |
| Ensign Peak Advisors, Inc | 559,744 | $13,574 |
| Caption Management, LLC | 125,309 | $3,039 |
| Schonfeld Strategic Advisors LLC | 172,696 | $4,188 |
| J. Goldman & Co LP | 13,105 | $318 |
| abrdn plc | 53,574 | $1,299 |
| OMERS ADMINISTRATION Corp | 17,500 | $424 |
| Pictet Asset Management Holding SA | 13,869 | $336 |
| GROUP ONE TRADING, L.P. | 2,461 | $60 |
| Washington Trust Advisors, Inc. | 184 | $4 |
| PRINCIPAL SECURITIES, INC. | 17 | $0 |
| SIMPLEX TRADING, LLC | 2,622 | $0 |