DAY ONE BIOPHARMACEUTICALS I

Ticker: DAWN CUSIP: 23954D109 Class: Common Stock

Note: Option positions (PUT/CALL) are excluded.

New Positions (40)

Increased Positions (71)

AIGH Capital Management LLC
Value ($000) $18,566 (+73.2%) Shares 1,992,021 (+31.0%)
Vestal Point Capital, LP
Value ($000) $48,464 (+157.0%) Shares 5,200,000 (+94.4%)
Parkman Healthcare Partners LLC
Value ($000) $6,016 (+182.8%) Shares 645,544 (+113.9%)
Pale Fire Capital SE
Value ($000) $5,071 (+137.8%) Shares 544,063 (+79.9%)
Hennion & Walsh Asset Management, Inc.
Value ($000) $2,921 (+335.9%) Shares 313,455 (+229.7%)
Jump Financial, LLC
Value ($000) $6,218 (+223.6%) Shares 667,120 (+144.8%)
Virtus Investment Advisers, LLC
Value ($000) $762 (+62.7%) Shares 81,747 (+23.1%)
GC Wealth Management RIA, LLC
Value ($000) $1,398 (+296.7%) Shares 150,030 (+200.1%)
AXQ CAPITAL, LP
Value ($000) $302 (+162.7%) Shares 32,405 (+98.7%)
PERKINS CAPITAL MANAGEMENT INC
Value ($000) $783 (+35.0%) Shares 84,000 (+2.1%)
Hudson Bay Capital Management LP
Value ($000) $15,844 (+70.3%) Shares 1,700,000 (+28.8%)
Schonfeld Strategic Advisors LLC
Value ($000) $2,797 (+1601.3%) Shares 300,102 (+1186.9%)
XTX Topco Ltd
Value ($000) $1,197 (+115.3%) Shares 128,440 (+62.9%)
Pictet Asset Management Holding SA
Value ($000) $27,874 (+66.6%) Shares 2,990,801 (+26.0%)
RENAISSANCE TECHNOLOGIES LLC
Value ($000) $12,163 (+90.5%) Shares 1,305,084 (+44.1%)
MILLENNIUM MANAGEMENT LLC
Value ($000) $12,581 (+157.4%) Shares 1,349,919 (+94.7%)
PROFUND ADVISORS LLC
Value ($000) $542 (+178.1%) Shares 58,129 (+110.3%)
FOX RUN MANAGEMENT, L.L.C.
Value ($000) $314 (+71.5%) Shares 33,639 (+29.7%)
Qube Research & Technologies Ltd
Value ($000) $13,855 (+68.3%) Shares 1,486,562 (+27.3%)
CITADEL ADVISORS LLC
Value ($000) $12,672 (+171.0%) Shares 1,359,613 (+105.0%)

Decreased Positions (41)

Stonepine Capital Management, LLC
Value ($000) $1,864 (-59.2%) Shares 200,000 (-69.1%)
MAK CAPITAL ONE LLC
Value ($000) $7,700 (-24.6%) Shares 826,205 (-43.0%)
Knott David M Jr
Value ($000) $241 (-73.8%) Shares 25,884 (-80.2%)
DEERFIELD MANAGEMENT COMPANY, L.P.
Value ($000) $34,700 (+4.6%) Shares 3,723,131 (-20.9%)
AlphaQuest LLC
Value ($000) $329 (-74.8%) Shares 35,326 (-80.9%)
ALGERT GLOBAL LLC
Value ($000) $5 (-46.3%) Shares 535,290 (-59.4%)
SPHERA FUNDS MANAGEMENT LTD.
Value ($000) $1,355 (+9.6%) Shares 145,371 (-17.1%)
FRANKLIN RESOURCES INC
Value ($000) $491 (-98.0%) Shares 52,726 (-98.5%)
FMR LLC
Value ($000) $53,283 (-25.2%) Shares 5,717,008 (-43.4%)
Susquehanna Portfolio Strategies, LLC
Value ($000) $535 (-18.0%) Shares 57,379 (-38.0%)
DRW Securities, LLC
Value ($000) $108 (-53.4%) Shares 11,635 (-65.0%)
DIMENSIONAL FUND ADVISORS LP
Value ($000) $9,667 (+12.1%) Shares 1,037,312 (-15.2%)
BlackRock, Inc.
Value ($000) $82,366 (+29.8%) Shares 8,837,574 (-1.8%)
BANK OF AMERICA CORP /DE/
Value ($000) $10,101 (+20.2%) Shares 1,083,818 (-9.1%)
Bank of New York Mellon Corp
Value ($000) $1,972 (-8.7%) Shares 211,546 (-30.9%)
HSBC HOLDINGS PLC
Value ($000) $455 (-41.0%) Shares 49,333 (-55.1%)
ExodusPoint Capital Management, LP
Value ($000) $366 (-14.7%) Shares 39,321 (-35.5%)
D. E. Shaw & Co., Inc.
Value ($000) $204 (-62.8%) Shares 21,919 (-71.9%)
Tower Research Capital LLC (TRC)
Value ($000) $15 (-83.6%) Shares 1,634 (-87.6%)
ROYAL BANK OF CANADA
Value ($000) $38 (-87.7%) Shares 4,108 (-90.7%)

Exited Positions (32)