DISC MEDICINE INC

Ticker: IRON CUSIP: 254604101 Class: Common Stock

Siren, L.L.C.'s Holding History (CIK: 0002005245)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 988,401 Value ($000) $78,489 Avg Close $84.50 Range $65.26 - $99.50

Q3 2025

Shares 913,401 Value ($000) $60,358 Avg Close $59.49 Range $51.01 - $68.43

Q2 2025

Shares 1,099,401 Value ($000) $58,224 Avg Close $46.97 Range $30.82 - $55.52

Q1 2025

Shares 1,071,865 Value ($000) $53,207 Avg Close $55.60 Range $48.05 - $65.02

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	988,401	$78,489	$84.50	$65.26 - $99.50
Q3 2025	913,401	$60,358	$59.49	$51.01 - $68.43
Q2 2025	1,099,401	$58,224	$46.97	$30.82 - $55.52
Q1 2025	1,071,865	$53,207	$55.60	$48.05 - $65.02