DYNE THERAPEUTICS INC

Ticker: DYN CUSIP: 26818M108 Class: Common Stock

Siren, L.L.C.'s Holding History (CIK: 0002005245)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 3,502,941 Value ($000) $68,518 Avg Close $18.94 Range $12.33 - $25.00

Q3 2025

Shares 4,729,174 Value ($000) $59,824 Avg Close $11.41 Range $8.06 - $14.35

Q2 2025

Shares 4,836,437 Value ($000) $46,043 Avg Close $11.01 Range $6.36 - $15.23

Q1 2025

Shares 2,717,987 Value ($000) $28,430 Avg Close $14.30 Range $9.96 - $26.22

Q4 2024

Shares 1,347,456 Value ($000) $31,746 Avg Close $29.58 Range $23.05 - $35.90

Q3 2024

Shares 1,134,664 Value ($000) $40,757 Avg Close $39.80 Range $23.55 - $47.45

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	3,502,941	$68,518	$18.94	$12.33 - $25.00
Q3 2025	4,729,174	$59,824	$11.41	$8.06 - $14.35
Q2 2025	4,836,437	$46,043	$11.01	$6.36 - $15.23
Q1 2025	2,717,987	$28,430	$14.30	$9.96 - $26.22
Q4 2024	1,347,456	$31,746	$29.58	$23.05 - $35.90
Q3 2024	1,134,664	$40,757	$39.80	$23.55 - $47.45