EDGEWISE THERAPEUTICS INC

Ticker: EWTX CUSIP: 28036F105 Class: Common Stock

Siren, L.L.C.'s Holding History (CIK: 0002005245)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 4,529,990 Value ($000) $112,412 Avg Close $20.07 Range $14.25 - $27.39

Q3 2025

Shares 3,897,099 Value ($000) $63,211 Avg Close $14.18 Range $12.30 - $17.00

Q2 2025

Shares 3,160,298 Value ($000) $41,432 Avg Close $14.42 Range $10.60 - $22.47

Q1 2025

Shares 1,696,444 Value ($000) $37,322 Avg Close $26.23 Range $21.52 - $30.48

Q4 2024

Shares 734,343 Value ($000) $19,607 Avg Close $31.84 Range $25.97 - $38.12

Q3 2024

Shares 404,113 Value ($000) $10,786 Avg Close $19.89 Range $15.02 - $30.00

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	4,529,990	$112,412	$20.07	$14.25 - $27.39
Q3 2025	3,897,099	$63,211	$14.18	$12.30 - $17.00
Q2 2025	3,160,298	$41,432	$14.42	$10.60 - $22.47
Q1 2025	1,696,444	$37,322	$26.23	$21.52 - $30.48
Q4 2024	734,343	$19,607	$31.84	$25.97 - $38.12
Q3 2024	404,113	$10,786	$19.89	$15.02 - $30.00