ENGENE HOLDINGS INC

Ticker: ENGN CUSIP: 29286M105 Class: COM

SPHERA FUNDS MANAGEMENT LTD.'s Holding History (CIK: 0001496201)

Note: Option positions (PUT/CALL) are excluded.

Q3 2025

Shares 504,409 Value ($000) $3,445 Avg Close $4.56 Range $3.25 - $7.33

Q2 2025

Shares 504,409 Value ($000) $1,836 Avg Close $3.75 Range $2.65 - $4.80

Q1 2025

Shares 528,365 Value ($000) $2,367 Avg Close $6.21 Range $4.20 - $8.44

Q4 2024

Shares 560,000 Value ($000) $3,724 Avg Close $7.77 Range $5.60 - $11.00

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2025	504,409	$3,445	$4.56	$3.25 - $7.33
Q2 2025	504,409	$1,836	$3.75	$2.65 - $4.80
Q1 2025	528,365	$2,367	$6.21	$4.20 - $8.44
Q4 2024	560,000	$3,724	$7.77	$5.60 - $11.00