GYRE THERAPEUTICS INC

Ticker: GYRE CUSIP: 403783103 Class: Common Stock

Holders for Q4 2025 Position Changes for Q4 2025

Note: Option positions (PUT/CALL) are excluded.

InstitutionSharesValue ($000)
VANGUARD GROUP INC1,201,589$8,483
BlackRock, Inc.720,291$5,085
GEODE CAPITAL MANAGEMENT, LLC423,222$2,989
STATE STREET CORP202,225$1,428
CHARLES SCHWAB INVESTMENT MANAGEMENT INC169,158$1,194
SBI Securities Co., Ltd.162,915$1,150
NORTHERN TRUST CORP128,855$910
MORGAN STANLEY54,498$385
Bank of New York Mellon Corp41,203$291
GOLDMAN SACHS GROUP INC31,108$220
STATE OF WISCONSIN INVESTMENT BOARD24,800$175
ALLIANCEBERNSTEIN L.P.21,830$154
STRS OHIO21,100$149
BARCLAYS PLC18,531$131
RHUMBLINE ADVISERS14,032$99
WELLS FARGO & COMPANY/MN12,919$91
ROYAL BANK OF CANADA12,765$91
DIMENSIONAL FUND ADVISORS LP10,903$77
DEUTSCHE BANK AG\10,613$75
FMR LLC10,304$73
BANK OF AMERICA CORP /DE/9,759$69
UBS Group AG9,584$68
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.5,481$39
State of Alaska, Department of Revenue5,219$0
JPMORGAN CHASE & CO5,113$36
NEW YORK STATE COMMON RETIREMENT FUND2,700$19
BNP PARIBAS ARBITRAGE, SA2,551$18
Police & Firemen's Retirement System of New Jersey2,097$15
Tower Research Capital LLC (TRC)2,077$15
Russell Investments Group, Ltd.2,003$14
Legal & General Group Plc1,405$10
SIMPLEX TRADING, LLC839$6
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM726$5
Ameritas Investment Partners, Inc.683$5
Activest Wealth Management533$4
AMALGAMATED BANK371$0
CITIGROUP INC268$2
Optiver Holding B.V.222$2
NISA INVESTMENT ADVISORS, LLC102$1
Sterling Capital Management LLC59$0
OSAIC HOLDINGS, INC.38$0
CWM, LLC36$0
Covestor Ltd6$0
Smartleaf Asset Management LLC6$0
Total (44 institutions)3,344,739$23,576