GYRE THERAPEUTICS INC

Ticker: GYRE CUSIP: 403783103 Class: Common Stock

Holders for Q4 2025 Position Changes for Q4 2025

Note: Option positions (PUT/CALL) are excluded.

New Positions (2)

DIMENSIONAL FUND ADVISORS LP
Value ($000) $77 Shares 10,903
Smartleaf Asset Management LLC
Value ($000) $0 Shares 6

Increased Positions (22)

BlackRock, Inc.
Value ($000) $5,085 (+3.4%) Shares 720,291 (+9.2%)
VANGUARD GROUP INC
Value ($000) $8,483 (-1.2%) Shares 1,201,589 (+4.4%)
GEODE CAPITAL MANAGEMENT, LLC
Value ($000) $2,989 (+6.9%) Shares 423,222 (+13.0%)
CHARLES SCHWAB INVESTMENT MANAGEMENT INC
Value ($000) $1,194 (+29.7%) Shares 169,158 (+37.1%)
MORGAN STANLEY
Value ($000) $385 (+474.3%) Shares 54,498 (+506.8%)
STATE STREET CORP
Value ($000) $1,428 (+4.7%) Shares 202,225 (+10.7%)
Bank of New York Mellon Corp
Value ($000) $291 (+59.8%) Shares 41,203 (+68.9%)
GOLDMAN SACHS GROUP INC
Value ($000) $220 (+63.2%) Shares 31,108 (+72.5%)
BARCLAYS PLC
Value ($000) $131 (+12.3%) Shares 18,531 (+99.5%)
NORTHERN TRUST CORP
Value ($000) $910 (+4.8%) Shares 128,855 (+10.8%)
WELLS FARGO & COMPANY/MN
Value ($000) $91 (+120.0%) Shares 12,919 (+132.4%)
BANK OF AMERICA CORP /DE/
Value ($000) $69 (+38.1%) Shares 9,759 (+45.9%)
JPMORGAN CHASE & CO
Value ($000) $36 (+31.0%) Shares 5,113 (+38.4%)
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.
Value ($000) $39 (+23.4%) Shares 5,481 (+30.4%)
Russell Investments Group, Ltd.
Value ($000) $14 (+68.6%) Shares 2,003 (+78.2%)
RHUMBLINE ADVISERS
Value ($000) $99 (-1.1%) Shares 14,032 (+4.5%)
Legal & General Group Plc
Value ($000) $10 (+53.7%) Shares 1,405 (+63.4%)
BNP PARIBAS ARBITRAGE, SA
Value ($000) $18 (+11.6%) Shares 2,551 (+17.9%)
ROYAL BANK OF CANADA
Value ($000) $91 (-1.1%) Shares 12,765 (+3.0%)
SIMPLEX TRADING, LLC
Value ($000) $6 (+592200.0%) Shares 839 (+411.6%)

Decreased Positions (8)

STATE OF WISCONSIN INVESTMENT BOARD
Value ($000) $175 (-39.8%) Shares 24,800 (-36.4%)
SBI Securities Co., Ltd.
Value ($000) $1,150 (-8.2%) Shares 162,915 (-2.9%)
UBS Group AG
Value ($000) $68 (-60.5%) Shares 9,584 (-58.3%)
Tower Research Capital LLC (TRC)
Value ($000) $15 (-27.0%) Shares 2,077 (-22.9%)
DEUTSCHE BANK AG\
Value ($000) $75 (-8.1%) Shares 10,613 (-2.9%)
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM
Value ($000) $5 (-19.0%) Shares 726 (-14.4%)
CITIGROUP INC
Value ($000) $2 (-33.9%) Shares 268 (-30.2%)
CWM, LLC
Value ($000) $0 Shares 36 (-16.3%)

Exited Positions (6)

MILLENNIUM MANAGEMENT LLC
Value ($000) $267 Shares 35,751
LAZARD ASSET MANAGEMENT LLC
Value ($000) $111 Shares 14,932
JANE STREET GROUP, LLC
Value ($000) $97 Shares 12,958
PRINCIPAL SECURITIES, INC.
Value ($000) $1 Shares 85
Advisory Services Network, LLC
Value ($000) $0 Shares 66
SRS Capital Advisors, Inc.
Value ($000) $0 Shares 57