IO BIOTECH INC

Ticker: IOBT CUSIP: 449778109 Class: COM

Holders for Q4 2025 Position Changes for Q4 2025

Note: Option positions (PUT/CALL) are excluded.

New Positions (5)

Dauntless Investment Group, LLC
Value ($000) $275 Shares 451,641
Beacon Pointe Advisors, LLC
Value ($000) $308 Shares 506,000
TWO SIGMA SECURITIES, LLC
Value ($000) $27 Shares 44,757
Scientech Research LLC
Value ($000) $7 Shares 11,255
ADAR1 Capital Management, LLC
Value ($000) $15 Shares 24,964

Increased Positions (3)

CITIGROUP INC
Value ($000) $68 (+14369.1%) Shares 111,447 (+8525.9%)
UBS Group AG
Value ($000) $27 (+942.4%) Shares 43,578 (+521.4%)
PKS Advisory Services, LLC
Value ($000) $12 (+72.0%) Shares 20,000 (+2.6%)

Decreased Positions (8)

Ikarian Capital, LLC
Value ($000) $844 (+52.4%) Shares 1,386,565 (-9.1%)
MILLENNIUM MANAGEMENT LLC
Value ($000) $84 (-83.3%) Shares 138,716 (-90.0%)
XTX Topco Ltd
Value ($000) $10 (-85.2%) Shares 15,864 (-91.1%)
MARSHALL WACE, LLP
Value ($000) $262 (-30.9%) Shares 429,338 (-59.2%)
RENAISSANCE TECHNOLOGIES LLC
Value ($000) $126 (-36.4%) Shares 207,601 (-62.1%)
BOOTHBAY FUND MANAGEMENT, LLC
Value ($000) $275 (+28.2%) Shares 451,852 (-23.6%)
MORGAN STANLEY
Value ($000) $328 (+35.3%) Shares 539,182 (-19.3%)
Virtu Financial LLC
Value ($000) $0 (-14.3%) Shares 19,078 (-51.2%)

Exited Positions (4)

Point72 Asset Management, L.P.
Value ($000) $91 Shares 250,000
Quadrature Capital Ltd
Value ($000) $30 Shares 83,382
GOLDMAN SACHS GROUP INC
Value ($000) $24 Shares 66,564
NewEdge Advisors, LLC
Value ($000) $9 Shares 25,692