IONIS PHARMACEUTICALS INC

Ticker: IONS CUSIP: 462222100 Class: COM

EcoR1 Capital, LLC's Holding History (CIK: 0001587114)

Note: Option positions (PUT/CALL) are excluded.

Q3 2024

Shares 500,000 Value ($000) $20,030 Avg Close $46.53 Range $39.48 - $52.34

Q1 2020

Shares 208,609 Value ($000) $9,863 Avg Close $55.74 Range $39.32 - $64.34

Q4 2018

Shares 725,326 Value ($000) $39,211 Avg Close $51.00 Range $43.27 - $59.81

Q3 2018

Shares 72,326 Value ($000) $3,731 Avg Close $46.98 Range $41.05 - $54.85

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2024	500,000	$20,030	$46.53	$39.48 - $52.34
Q1 2020	208,609	$9,863	$55.74	$39.32 - $64.34
Q4 2018	725,326	$39,211	$51.00	$43.27 - $59.81
Q3 2018	72,326	$3,731	$46.98	$41.05 - $54.85