KALVISTA PHARMACEUTICALS INC

Ticker: KALV CUSIP: 483497103 Class: Common Stock

SPHERA FUNDS MANAGEMENT LTD.'s Holding History (CIK: 0001496201)

Note: Option positions (PUT/CALL) are excluded.

Q4 2021

Shares 316,200 Value ($000) $4,183 Avg Close $15.92 Range $11.99 - $18.53

Q1 2021

Shares 258,880 Value ($000) $6,651 Avg Close $26.28 Range $14.33 - $45.00

Q4 2020

Shares 240,140 Value ($000) $4,560 Avg Close $17.15 Range $12.01 - $20.21

Q3 2020

Shares 240,140 Value ($000) $3,023 Avg Close $12.50 Range $9.62 - $14.46

Q2 2020

Shares 240,140 Value ($000) $2,906 Avg Close $10.63 Range $6.31 - $13.64

Q1 2020

Shares 240,140 Value ($000) $1,837 Avg Close $13.49 Range $5.61 - $18.96

Q4 2019

Shares 147,700 Value ($000) $2,631 Avg Close $13.05 Range $9.86 - $18.40

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2021	316,200	$4,183	$15.92	$11.99 - $18.53
Q1 2021	258,880	$6,651	$26.28	$14.33 - $45.00
Q4 2020	240,140	$4,560	$17.15	$12.01 - $20.21
Q3 2020	240,140	$3,023	$12.50	$9.62 - $14.46
Q2 2020	240,140	$2,906	$10.63	$6.31 - $13.64
Q1 2020	240,140	$1,837	$13.49	$5.61 - $18.96
Q4 2019	147,700	$2,631	$13.05	$9.86 - $18.40