KARYOPHARM THERAPEUTICS INC

Ticker: KPTI CUSIP: 48576U205 Class: 0

GROUP ONE TRADING, L.P.'s Holding History (CIK: 0000932540)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 102,419 Value ($000) $754 Avg Close $6.12 Range $4.51 - $7.70

Q3 2025

Shares 68,436 Value ($000) $448 Avg Close $5.38 Range $3.65 - $8.15

Q2 2025

Shares 97,900 Value ($000) $422 Avg Close $4.91 Range $3.51 - $7.90

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	102,419	$754	$6.12	$4.51 - $7.70
Q3 2025	68,436	$448	$5.38	$3.65 - $8.15
Q2 2025	97,900	$422	$4.91	$3.51 - $7.90