LEXICON PHARMACEUTICALS INC

Ticker: LXRX CUSIP: 528872302 Class: COM NEW

RENAISSANCE TECHNOLOGIES LLC's Holding History (CIK: 0001037389)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 263,254 Value ($000) $303 Avg Close $1.37 Range $1.12 - $1.66

Q3 2025

Shares 292,400 Value ($000) $395 Avg Close $1.13 Range $0.84 - $1.43

Q4 2024

Shares 51,141 Value ($000) $38 Avg Close $1.22 Range $0.62 - $2.17

Q4 2023

Shares 412,175 Value ($000) $1 Avg Close $1.19 Range $0.92 - $1.64

Q3 2023

Shares 272,255 Value ($000) $0 Avg Close $1.75 Range $1.04 - $2.38

Q1 2023

Shares 263,875 Value ($000) $1 Avg Close $2.29 Range $1.91 - $2.90

Q4 2022

Shares 393,285 Value ($000) $1 Avg Close $2.13 Range $1.71 - $2.57

Q3 2022

Shares 481,375 Value ($000) $1,155 Avg Close $2.77 Range $1.78 - $3.48

Q1 2022

Shares 88,776 Value ($000) $186 Avg Close $2.77 Range $1.87 - $3.99

Q2 2021

Shares 59,775 Value ($000) $274 Avg Close $4.82 Range $4.06 - $6.11

Q1 2021

Shares 312,479 Value ($000) $1,834 Avg Close $6.92 Range $3.32 - $9.65

Q4 2020

Shares 994,979 Value ($000) $3,403 Avg Close $1.91 Range $1.03 - $4.10

Q3 2020

Shares 1,632,631 Value ($000) $2,351 Avg Close $1.78 Range $1.42 - $2.89

Q2 2020

Shares 1,880,203 Value ($000) $3,751 Avg Close $1.96 Range $1.71 - $2.59

Q1 2020

Shares 1,666,598 Value ($000) $3,250 Avg Close $2.98 Range $1.70 - $4.47

Q4 2019

Shares 1,203,178 Value ($000) $4,993 Avg Close $3.85 Range $2.51 - $5.33

Q3 2019

Shares 665,379 Value ($000) $2,003 Avg Close $3.10 Range $1.13 - $6.72

Q2 2019

Shares 546,741 Value ($000) $3,439 Avg Close $5.99 Range $5.10 - $7.27

Q1 2019

Shares 489,513 Value ($000) $2,722 Avg Close $6.10 Range $4.25 - $8.39

Q4 2018

Shares 344,486 Value ($000) $2,287 Avg Close $8.10 Range $6.02 - $10.99

Q3 2018

Shares 91,586 Value ($000) $977 Avg Close $11.46 Range $10.24 - $13.31

Q2 2018

Shares 192,426 Value ($000) $2,309 Avg Close $10.23 Range $7.67 - $13.97

Q1 2018

Shares 229,086 Value ($000) $1,963 Avg Close $9.25 Range $7.80 - $11.58

Q4 2017

Shares 504,886 Value ($000) $4,988 Avg Close $10.39 Range $8.07 - $12.38

Q3 2017

Shares 288,086 Value ($000) $3,541 Avg Close $14.77 Range $11.80 - $17.29

Q2 2017

Shares 384,097 Value ($000) $6,318 Avg Close $15.48 Range $13.48 - $18.00

Q1 2017

Shares 261,505 Value ($000) $3,750 Avg Close $14.84 Range $13.41 - $17.48

Q3 2015

Shares 11,086 Value ($000) $119 Avg Close $10.92 Range $7.85 - $15.79

Q2 2015

Shares 170,153 Value ($000) $1,370 Avg Close $7.34 Range $6.30 - $8.49

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	263,254	$303	$1.37	$1.12 - $1.66
Q3 2025	292,400	$395	$1.13	$0.84 - $1.43
Q4 2024	51,141	$38	$1.22	$0.62 - $2.17
Q4 2023	412,175	$1	$1.19	$0.92 - $1.64
Q3 2023	272,255	$0	$1.75	$1.04 - $2.38
Q1 2023	263,875	$1	$2.29	$1.91 - $2.90
Q4 2022	393,285	$1	$2.13	$1.71 - $2.57
Q3 2022	481,375	$1,155	$2.77	$1.78 - $3.48
Q1 2022	88,776	$186	$2.77	$1.87 - $3.99
Q2 2021	59,775	$274	$4.82	$4.06 - $6.11
Q1 2021	312,479	$1,834	$6.92	$3.32 - $9.65
Q4 2020	994,979	$3,403	$1.91	$1.03 - $4.10
Q3 2020	1,632,631	$2,351	$1.78	$1.42 - $2.89
Q2 2020	1,880,203	$3,751	$1.96	$1.71 - $2.59
Q1 2020	1,666,598	$3,250	$2.98	$1.70 - $4.47
Q4 2019	1,203,178	$4,993	$3.85	$2.51 - $5.33
Q3 2019	665,379	$2,003	$3.10	$1.13 - $6.72
Q2 2019	546,741	$3,439	$5.99	$5.10 - $7.27
Q1 2019	489,513	$2,722	$6.10	$4.25 - $8.39
Q4 2018	344,486	$2,287	$8.10	$6.02 - $10.99
Q3 2018	91,586	$977	$11.46	$10.24 - $13.31
Q2 2018	192,426	$2,309	$10.23	$7.67 - $13.97
Q1 2018	229,086	$1,963	$9.25	$7.80 - $11.58
Q4 2017	504,886	$4,988	$10.39	$8.07 - $12.38
Q3 2017	288,086	$3,541	$14.77	$11.80 - $17.29
Q2 2017	384,097	$6,318	$15.48	$13.48 - $18.00
Q1 2017	261,505	$3,750	$14.84	$13.41 - $17.48
Q3 2015	11,086	$119	$10.92	$7.85 - $15.79
Q2 2015	170,153	$1,370	$7.34	$6.30 - $8.49