LIGAND PHARMACEUTICALS INC

Ticker: LGND CUSIP: 53220K504 Class: Common Stock

Opaleye Management Inc.'s Holding History (CIK: 0001595855)

Note: Option positions (PUT/CALL) are excluded.

Q1 2014

Shares 35,000 Value ($000) $2,354 Avg Close $41.68 Range $31.65 - $50.17

Q4 2013

Shares 90,000 Value ($000) $4,860,000 Avg Close $32.58 Range $26.95 - $36.48

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2014	35,000	$2,354	$41.68	$31.65 - $50.17
Q4 2013	90,000	$4,860,000	$32.58	$26.95 - $36.48