MBX BIOSCIENCES INC

Ticker: MBX CUSIP: 55287L101 Class: Common Stock

ORBIMED ADVISORS LLC's Holding History (CIK: 0001055951)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 3,935,203 Value ($000) $124,116 Avg Close $24.26 Range $12.94 - $35.55

Q3 2025

Shares 4,002,887 Value ($000) $70,051 Avg Close $13.37 Range $9.63 - $26.47

Q2 2025

Shares 4,002,887 Value ($000) $45,673 Avg Close $10.19 Range $4.81 - $14.34

Q1 2025

Shares 4,002,887 Value ($000) $29,541 Avg Close $10.57 Range $7.16 - $19.39

Q4 2024

Shares 3,812,215 Value ($000) $70,259 Avg Close $21.31 Range $15.31 - $27.50

Q3 2024

Shares 3,812,215 Value ($000) $99,041 Avg Close $22.87 Range $20.29 - $26.19

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	3,935,203	$124,116	$24.26	$12.94 - $35.55
Q3 2025	4,002,887	$70,051	$13.37	$9.63 - $26.47
Q2 2025	4,002,887	$45,673	$10.19	$4.81 - $14.34
Q1 2025	4,002,887	$29,541	$10.57	$7.16 - $19.39
Q4 2024	3,812,215	$70,259	$21.31	$15.31 - $27.50
Q3 2024	3,812,215	$99,041	$22.87	$20.29 - $26.19