MBX BIOSCIENCES INC

Ticker: MBX CUSIP: 55287L101 Class: Common Stock

Opaleye Management Inc.'s Holding History (CIK: 0001595855)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 260,000 Value ($000) $8,200 Avg Close $24.26 Range $12.94 - $35.55

Q3 2025

Shares 253,000 Value ($000) $4,428 Avg Close $13.37 Range $9.63 - $26.47

Q2 2025

Shares 239,319 Value ($000) $2,731 Avg Close $10.19 Range $4.81 - $14.34

Q1 2025

Shares 250,000 Value ($000) $1,845 Avg Close $10.57 Range $7.16 - $19.39

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	260,000	$8,200	$24.26	$12.94 - $35.55
Q3 2025	253,000	$4,428	$13.37	$9.63 - $26.47
Q2 2025	239,319	$2,731	$10.19	$4.81 - $14.34
Q1 2025	250,000	$1,845	$10.57	$7.16 - $19.39