MBX BIOSCIENCES INC

Ticker: MBX CUSIP: 55287L101 Class: Common Stock

Frazier Life Sciences Management, L.P.'s Holding History (CIK: 0001892134)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 6,652,013 Value ($000) $209,804 Avg Close $24.26 Range $12.94 - $35.55

Q3 2025

Shares 6,652,013 Value ($000) $116,410 Avg Close $13.37 Range $9.63 - $26.47

Q2 2025

Shares 5,985,347 Value ($000) $68,293 Avg Close $10.19 Range $4.81 - $14.34

Q1 2025

Shares 5,985,347 Value ($000) $44,172 Avg Close $10.57 Range $7.16 - $19.39

Q4 2024

Shares 5,985,347 Value ($000) $110,310 Avg Close $21.31 Range $15.31 - $27.50

Q3 2024

Shares 5,985,347 Value ($000) $155,499 Avg Close $22.87 Range $20.29 - $26.19

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	6,652,013	$209,804	$24.26	$12.94 - $35.55
Q3 2025	6,652,013	$116,410	$13.37	$9.63 - $26.47
Q2 2025	5,985,347	$68,293	$10.19	$4.81 - $14.34
Q1 2025	5,985,347	$44,172	$10.57	$7.16 - $19.39
Q4 2024	5,985,347	$110,310	$21.31	$15.31 - $27.50
Q3 2024	5,985,347	$155,499	$22.87	$20.29 - $26.19