MADRIGAL PHARMACEUTICALS INC

Ticker: MDGL CUSIP: 558868105 Class: EQTY

Squarepoint Ops LLC's Holding History (CIK: 0001642575)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 74,934 Value ($000) $43,637 Avg Close $510.76 Range $393.61 - $615.00

Q3 2025

Shares 29,936 Value ($000) $13,730 Avg Close $373.08 Range $284.02 - $460.22

Q2 2025

Shares 4,382 Value ($000) $1,326 Avg Close $297.95 Range $265.00 - $349.00

Q1 2025

Shares 1,648 Value ($000) $546 Avg Close $328.59 Range $266.44 - $377.46

Q4 2024

Shares 1,548 Value ($000) $478 Avg Close $281.26 Range $200.63 - $368.29

Q2 2024

Shares 5,170 Value ($000) $1,448 Avg Close $238.04 Range $189.00 - $295.50

Q4 2022

Shares 2,932 Value ($000) $851 Avg Close $97.80 Range $57.21 - $315.45

Q2 2022

Shares 4,074 Value ($000) $292 Avg Close $73.50 Range $57.15 - $100.90

Q4 2021

Shares 22,827 Value ($000) $1,934 Avg Close $82.16 Range $68.56 - $102.42

Q3 2021

Shares 35,115 Value ($000) $2,802 Avg Close $86.38 Range $77.60 - $105.72

Q2 2021

Shares 32,587 Value ($000) $3,174 Avg Close $118.38 Range $95.21 - $142.62

Q1 2021

Shares 19,464 Value ($000) $2,277 Avg Close $116.59 Range $105.16 - $131.99

Q4 2020

Shares 3,112 Value ($000) $346 Avg Close $122.23 Range $107.55 - $137.28

Q3 2020

Shares 4,753 Value ($000) $564 Avg Close $108.57 Range $98.65 - $125.06

Q2 2020

Shares 2,990 Value ($000) $339 Avg Close $98.34 Range $56.82 - $127.25

Q4 2019

Shares 21,301 Value ($000) $1,941 Avg Close $96.98 Range $82.31 - $121.21

Q3 2019

Shares 3,892 Value ($000) $336 Avg Close $93.82 Range $82.39 - $108.37

Q1 2019

Shares 2,300 Value ($000) $288 Avg Close $124.30 Range $102.43 - $148.18

Q4 2018

Shares 2,472 Value ($000) $279 Avg Close $154.76 Range $91.56 - $222.29

Q3 2018

Shares 4,051 Value ($000) $867 Avg Close $250.94 Range $193.57 - $315.00

Q2 2018

Shares 1,600 Value ($000) $448 Avg Close $175.60 Range $98.81 - $325.98

Q1 2018

Shares 3,792 Value ($000) $443 Avg Close $123.44 Range $90.56 - $154.75

Q4 2017

Shares 3,925 Value ($000) $360 Avg Close $57.12 Range $38.82 - $101.00

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	74,934	$43,637	$510.76	$393.61 - $615.00
Q3 2025	29,936	$13,730	$373.08	$284.02 - $460.22
Q2 2025	4,382	$1,326	$297.95	$265.00 - $349.00
Q1 2025	1,648	$546	$328.59	$266.44 - $377.46
Q4 2024	1,548	$478	$281.26	$200.63 - $368.29
Q2 2024	5,170	$1,448	$238.04	$189.00 - $295.50
Q4 2022	2,932	$851	$97.80	$57.21 - $315.45
Q2 2022	4,074	$292	$73.50	$57.15 - $100.90
Q4 2021	22,827	$1,934	$82.16	$68.56 - $102.42
Q3 2021	35,115	$2,802	$86.38	$77.60 - $105.72
Q2 2021	32,587	$3,174	$118.38	$95.21 - $142.62
Q1 2021	19,464	$2,277	$116.59	$105.16 - $131.99
Q4 2020	3,112	$346	$122.23	$107.55 - $137.28
Q3 2020	4,753	$564	$108.57	$98.65 - $125.06
Q2 2020	2,990	$339	$98.34	$56.82 - $127.25
Q4 2019	21,301	$1,941	$96.98	$82.31 - $121.21
Q3 2019	3,892	$336	$93.82	$82.39 - $108.37
Q1 2019	2,300	$288	$124.30	$102.43 - $148.18
Q4 2018	2,472	$279	$154.76	$91.56 - $222.29
Q3 2018	4,051	$867	$250.94	$193.57 - $315.00
Q2 2018	1,600	$448	$175.60	$98.81 - $325.98
Q1 2018	3,792	$443	$123.44	$90.56 - $154.75
Q4 2017	3,925	$360	$57.12	$38.82 - $101.00