MAZE THERAPEUTICS INC

Ticker: MAZE CUSIP: 578784100 Class: Common Stock

SPHERA FUNDS MANAGEMENT LTD.'s Holding History (CIK: 0001496201)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 71,843 Value ($000) $2,976 Avg Close $34.37 Range $24.99 - $43.29

Q3 2025

Shares 154,343 Value ($000) $4,002 Avg Close $16.88 Range $10.98 - $28.37

Q2 2025

Shares 356,453 Value ($000) $4,374 Avg Close $10.40 Range $6.71 - $14.40

Q1 2025

Shares 355,554 Value ($000) $3,915 Avg Close $12.04 Range $9.88 - $17.00

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	71,843	$2,976	$34.37	$24.99 - $43.29
Q3 2025	154,343	$4,002	$16.88	$10.98 - $28.37
Q2 2025	356,453	$4,374	$10.40	$6.71 - $14.40
Q1 2025	355,554	$3,915	$12.04	$9.88 - $17.00