MAZE THERAPEUTICS INC

Ticker: MAZE CUSIP: 578784100 Class: Common Stock

Frazier Life Sciences Management, L.P.'s Holding History (CIK: 0001892134)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 4,567,274 Value ($000) $189,222 Avg Close $34.37 Range $24.99 - $43.29

Q3 2025

Shares 4,567,274 Value ($000) $118,429 Avg Close $16.88 Range $10.98 - $28.37

Q2 2025

Shares 4,567,275 Value ($000) $56,040 Avg Close $10.40 Range $6.71 - $14.40

Q1 2025

Shares 4,129,001 Value ($000) $45,460 Avg Close $12.04 Range $9.88 - $17.00

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	4,567,274	$189,222	$34.37	$24.99 - $43.29
Q3 2025	4,567,274	$118,429	$16.88	$10.98 - $28.37
Q2 2025	4,567,275	$56,040	$10.40	$6.71 - $14.40
Q1 2025	4,129,001	$45,460	$12.04	$9.88 - $17.00