MINERALYS THERAPEUTICS INC

Ticker: MLYS CUSIP: 603170101 Class: Common Stock

ORBIMED ADVISORS LLC's Holding History (CIK: 0001055951)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 980,400 Value ($000) $35,579 Avg Close $40.10 Range $33.63 - $47.65

Q3 2025

Shares 1,469,494 Value ($000) $55,723 Avg Close $21.63 Range $12.59 - $41.09

Q2 2025

Shares 760,351 Value ($000) $10,288 Avg Close $14.49 Range $10.44 - $17.17

Q4 2024

Shares 1,611,637 Value ($000) $19,839 Avg Close $13.08 Range $11.19 - $15.25

Q3 2024

Shares 2,002,939 Value ($000) $24,256 Avg Close $12.11 Range $8.58 - $15.12

Q2 2024

Shares 2,021,424 Value ($000) $23,651 Avg Close $12.59 Range $10.37 - $15.00

Q1 2024

Shares 2,021,424 Value ($000) $26,097 Avg Close $12.35 Range $7.95 - $16.91

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	980,400	$35,579	$40.10	$33.63 - $47.65
Q3 2025	1,469,494	$55,723	$21.63	$12.59 - $41.09
Q2 2025	760,351	$10,288	$14.49	$10.44 - $17.17
Q4 2024	1,611,637	$19,839	$13.08	$11.19 - $15.25
Q3 2024	2,002,939	$24,256	$12.11	$8.58 - $15.12
Q2 2024	2,021,424	$23,651	$12.59	$10.37 - $15.00
Q1 2024	2,021,424	$26,097	$12.35	$7.95 - $16.91