MINERALYS THERAPEUTICS INC

Ticker: MLYS CUSIP: 603170101 Class: Common Stock

SPHERA FUNDS MANAGEMENT LTD.'s Holding History (CIK: 0001496201)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 449,003 Value ($000) $16,294 Avg Close $40.10 Range $33.63 - $47.65

Q3 2025

Shares 219,910 Value ($000) $8,339 Avg Close $21.63 Range $12.59 - $41.09

Q2 2025

Shares 480,974 Value ($000) $6,508 Avg Close $14.49 Range $10.44 - $17.17

Q1 2025

Shares 465,526 Value ($000) $7,393 Avg Close $11.50 Range $8.24 - $18.38

Q4 2024

Shares 190,672 Value ($000) $2,347 Avg Close $13.08 Range $11.19 - $15.25

Q3 2024

Shares 272,472 Value ($000) $3,300 Avg Close $12.11 Range $8.58 - $15.12

Q2 2024

Shares 442,752 Value ($000) $5,180 Avg Close $12.59 Range $10.37 - $15.00

Q1 2024

Shares 658,803 Value ($000) $8,505 Avg Close $12.35 Range $7.95 - $16.91

Q4 2023

Shares 743,591 Value ($000) $6,395 Avg Close $7.85 Range $5.85 - $10.09

Q3 2023

Shares 455,400 Value ($000) $4,331 Avg Close $13.04 Range $8.87 - $17.05

Q2 2023

Shares 405,400 Value ($000) $6,912 Avg Close $14.95 Range $12.62 - $17.70

Q1 2023

Shares 339,000 Value ($000) $5,309 Avg Close $16.83 Range $13.52 - $21.98

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	449,003	$16,294	$40.10	$33.63 - $47.65
Q3 2025	219,910	$8,339	$21.63	$12.59 - $41.09
Q2 2025	480,974	$6,508	$14.49	$10.44 - $17.17
Q1 2025	465,526	$7,393	$11.50	$8.24 - $18.38
Q4 2024	190,672	$2,347	$13.08	$11.19 - $15.25
Q3 2024	272,472	$3,300	$12.11	$8.58 - $15.12
Q2 2024	442,752	$5,180	$12.59	$10.37 - $15.00
Q1 2024	658,803	$8,505	$12.35	$7.95 - $16.91
Q4 2023	743,591	$6,395	$7.85	$5.85 - $10.09
Q3 2023	455,400	$4,331	$13.04	$8.87 - $17.05
Q2 2023	405,400	$6,912	$14.95	$12.62 - $17.70
Q1 2023	339,000	$5,309	$16.83	$13.52 - $21.98