MONOPAR THERAPEUTICS INC

Ticker: MNPR CUSIP: 61023L207 Class: Common Stock

Siren, L.L.C.'s Holding History (CIK: 0002005245)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 212,298 Value ($000) $13,863 Avg Close $81.71 Range $63.73 - $105.00

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	212,298	$13,863	$81.71	$63.73 - $105.00