NEUROCRINE BIOSCIENCES INC

Ticker: NBIX CUSIP: 64125C109 Class: EQTY

ROYAL BANK OF CANADA's Holding History (CIK: 0001000275)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 311,012 Value ($000) $44,110 Avg Close $144.87 Range $133.61 - $160.18

Q3 2025

Shares 244,676 Value ($000) $34,349 Avg Close $135.50 Range $123.67 - $148.00

Q2 2025

Shares 121,152 Value ($000) $15,227 Avg Close $114.68 Range $84.23 - $130.46

Q1 2025

Shares 82,810 Value ($000) $9,158 Avg Close $126.68 Range $105.18 - $154.61

Q4 2024

Shares 60,586 Value ($000) $8,269 Avg Close $123.68 Range $110.95 - $140.00

Q3 2024

Shares 252,910 Value ($000) $29,140 Avg Close $137.09 Range $114.08 - $157.98

Q2 2024

Shares 165,429 Value ($000) $22,774 Avg Close $137.14 Range $129.33 - $145.78

Q1 2024

Shares 138,974 Value ($000) $19,166 Avg Close $136.57 Range $128.00 - $148.37

Q4 2023

Shares 122,547 Value ($000) $16,145 Avg Close $115.11 Range $103.63 - $133.64

Q3 2023

Shares 48,128 Value ($000) $5,413 Avg Close $105.30 Range $93.28 - $119.29

Q2 2023

Shares 43,895 Value ($000) $4,139 Avg Close $97.71 Range $89.04 - $107.98

Q1 2023

Shares 117,723 Value ($000) $11,915 Avg Close $104.06 Range $92.89 - $125.02

Q4 2022

Shares 121,352 Value ($000) $14,495 Avg Close $117.13 Range $105.14 - $129.29

Q3 2022

Shares 113,898 Value ($000) $12,098 Avg Close $101.46 Range $91.53 - $109.26

Q2 2022

Shares 107,925 Value ($000) $10,521 Avg Close $92.29 Range $75.25 - $100.73

Q1 2022

Shares 71,335 Value ($000) $6,687 Avg Close $84.75 Range $71.88 - $95.87

Q4 2021

Shares 61,525 Value ($000) $5,240 Avg Close $91.99 Range $78.31 - $108.02

Q3 2021

Shares 59,748 Value ($000) $5,731 Avg Close $94.46 Range $84.77 - $101.43

Q2 2021

Shares 67,479 Value ($000) $6,566 Avg Close $95.85 Range $87.19 - $103.72

Q1 2021

Shares 61,823 Value ($000) $6,013 Avg Close $104.86 Range $87.37 - $120.27

Q4 2020

Shares 57,581 Value ($000) $5,519 Avg Close $96.59 Range $86.02 - $108.93

Q3 2020

Shares 41,790 Value ($000) $4,018 Avg Close $115.68 Range $95.42 - $136.26

Q2 2020

Shares 29,668 Value ($000) $3,619 Avg Close $110.51 Range $82.51 - $131.00

Q1 2020

Shares 27,652 Value ($000) $2,393 Avg Close $97.87 Range $72.14 - $115.24

Q4 2019

Shares 29,408 Value ($000) $3,161 Avg Close $104.70 Range $84.68 - $119.65

Q3 2019

Shares 25,260 Value ($000) $2,277 Avg Close $93.43 Range $83.19 - $102.51

Q2 2019

Shares 23,141 Value ($000) $1,954 Avg Close $82.11 Range $71.85 - $91.98

Q1 2019

Shares 24,054 Value ($000) $2,119 Avg Close $83.58 Range $67.10 - $92.71

Q4 2018

Shares 23,540 Value ($000) $1,680 Avg Close $95.81 Range $64.72 - $125.59

Q3 2018

Shares 13,078 Value ($000) $1,608 Avg Close $113.46 Range $96.98 - $126.98

Q2 2018

Shares 11,836 Value ($000) $1,163 Avg Close $89.51 Range $74.34 - $106.26

Q1 2018

Shares 11,350 Value ($000) $941 Avg Close $84.45 Range $74.12 - $92.98

Q4 2017

Shares 7,922 Value ($000) $615 Avg Close $68.21 Range $57.71 - $78.05

Q3 2017

Shares 159,730 Value ($000) $9,788 Avg Close $52.77 Range $44.75 - $61.51

Q2 2017

Shares 161,531 Value ($000) $7,431 Avg Close $48.51 Range $39.21 - $55.38

Q1 2017

Shares 214,478 Value ($000) $9,287 Avg Close $42.84 Range $38.38 - $47.43

Q4 2016

Shares 8,868 Value ($000) $344 Avg Close $45.27 Range $37.35 - $54.91

Q3 2016

Shares 36,225 Value ($000) $1,833 Avg Close $49.80 Range $44.69 - $55.15

Q2 2016

Shares 477,152 Value ($000) $21,686 Avg Close $46.04 Range $39.01 - $53.00

Q1 2016

Shares 462,703 Value ($000) $18,298 Avg Close $39.68 Range $31.25 - $55.94

Q4 2015

Shares 408,358 Value ($000) $23,101 Avg Close $50.83 Range $37.76 - $58.46

Q3 2015

Shares 10,391 Value ($000) $414 Avg Close $48.33 Range $33.61 - $56.97

Q2 2015

Shares 26,000 Value ($000) $1,242 Avg Close $42.40 Range $32.67 - $49.49

Q1 2015

Shares 17,600 Value ($000) $699 Avg Close $35.77 Range $19.68 - $45.36

Q4 2014

Shares 63,795 Value ($000) $1,425 Avg Close $18.95 Range $15.20 - $24.86

Q3 2014

Shares 6,100 Value ($000) $96 Avg Close $14.95 Range $12.63 - $17.00

Q2 2014

Shares 6,100 Value ($000) $91 Avg Close $14.11 Range $12.17 - $16.47

Q1 2014

Shares 6,100 Value ($000) $98 Avg Close $17.10 Range $9.19 - $20.29

Q4 2013

Shares 1,100 Value ($000) $10 Avg Close $9.76 Range $8.57 - $11.88

Q3 2013

Shares 3,200 Value ($000) $36 Avg Close $13.75 Range $10.42 - $16.74

Q2 2013

Shares 4,700 Value ($000) $63 Avg Close $12.28 Range $10.87 - $14.06

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	311,012	$44,110	$144.87	$133.61 - $160.18
Q3 2025	244,676	$34,349	$135.50	$123.67 - $148.00
Q2 2025	121,152	$15,227	$114.68	$84.23 - $130.46
Q1 2025	82,810	$9,158	$126.68	$105.18 - $154.61
Q4 2024	60,586	$8,269	$123.68	$110.95 - $140.00
Q3 2024	252,910	$29,140	$137.09	$114.08 - $157.98
Q2 2024	165,429	$22,774	$137.14	$129.33 - $145.78
Q1 2024	138,974	$19,166	$136.57	$128.00 - $148.37
Q4 2023	122,547	$16,145	$115.11	$103.63 - $133.64
Q3 2023	48,128	$5,413	$105.30	$93.28 - $119.29
Q2 2023	43,895	$4,139	$97.71	$89.04 - $107.98
Q1 2023	117,723	$11,915	$104.06	$92.89 - $125.02
Q4 2022	121,352	$14,495	$117.13	$105.14 - $129.29
Q3 2022	113,898	$12,098	$101.46	$91.53 - $109.26
Q2 2022	107,925	$10,521	$92.29	$75.25 - $100.73
Q1 2022	71,335	$6,687	$84.75	$71.88 - $95.87
Q4 2021	61,525	$5,240	$91.99	$78.31 - $108.02
Q3 2021	59,748	$5,731	$94.46	$84.77 - $101.43
Q2 2021	67,479	$6,566	$95.85	$87.19 - $103.72
Q1 2021	61,823	$6,013	$104.86	$87.37 - $120.27
Q4 2020	57,581	$5,519	$96.59	$86.02 - $108.93
Q3 2020	41,790	$4,018	$115.68	$95.42 - $136.26
Q2 2020	29,668	$3,619	$110.51	$82.51 - $131.00
Q1 2020	27,652	$2,393	$97.87	$72.14 - $115.24
Q4 2019	29,408	$3,161	$104.70	$84.68 - $119.65
Q3 2019	25,260	$2,277	$93.43	$83.19 - $102.51
Q2 2019	23,141	$1,954	$82.11	$71.85 - $91.98
Q1 2019	24,054	$2,119	$83.58	$67.10 - $92.71
Q4 2018	23,540	$1,680	$95.81	$64.72 - $125.59
Q3 2018	13,078	$1,608	$113.46	$96.98 - $126.98
Q2 2018	11,836	$1,163	$89.51	$74.34 - $106.26
Q1 2018	11,350	$941	$84.45	$74.12 - $92.98
Q4 2017	7,922	$615	$68.21	$57.71 - $78.05
Q3 2017	159,730	$9,788	$52.77	$44.75 - $61.51
Q2 2017	161,531	$7,431	$48.51	$39.21 - $55.38
Q1 2017	214,478	$9,287	$42.84	$38.38 - $47.43
Q4 2016	8,868	$344	$45.27	$37.35 - $54.91
Q3 2016	36,225	$1,833	$49.80	$44.69 - $55.15
Q2 2016	477,152	$21,686	$46.04	$39.01 - $53.00
Q1 2016	462,703	$18,298	$39.68	$31.25 - $55.94
Q4 2015	408,358	$23,101	$50.83	$37.76 - $58.46
Q3 2015	10,391	$414	$48.33	$33.61 - $56.97
Q2 2015	26,000	$1,242	$42.40	$32.67 - $49.49
Q1 2015	17,600	$699	$35.77	$19.68 - $45.36
Q4 2014	63,795	$1,425	$18.95	$15.20 - $24.86
Q3 2014	6,100	$96	$14.95	$12.63 - $17.00
Q2 2014	6,100	$91	$14.11	$12.17 - $16.47
Q1 2014	6,100	$98	$17.10	$9.19 - $20.29
Q4 2013	1,100	$10	$9.76	$8.57 - $11.88
Q3 2013	3,200	$36	$13.75	$10.42 - $16.74
Q2 2013	4,700	$63	$12.28	$10.87 - $14.06