NEUROCRINE BIOSCIENCES INC

Ticker: NBIX CUSIP: 64125C109 Class: EQTY

ORBIMED ADVISORS LLC's Holding History (CIK: 0001055951)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 314,240 Value ($000) $44,569 Avg Close $144.87 Range $133.61 - $160.18

Q3 2025

Shares 353,640 Value ($000) $49,644 Avg Close $135.50 Range $123.67 - $148.00

Q2 2025

Shares 438,540 Value ($000) $55,120 Avg Close $114.68 Range $84.23 - $130.46

Q1 2025

Shares 934,640 Value ($000) $103,371 Avg Close $126.68 Range $105.18 - $154.61

Q4 2024

Shares 938,120 Value ($000) $128,053 Avg Close $123.68 Range $110.95 - $140.00

Q3 2024

Shares 302,220 Value ($000) $34,822 Avg Close $137.09 Range $114.08 - $157.98

Q2 2024

Shares 448,200 Value ($000) $61,704 Avg Close $137.14 Range $129.33 - $145.78

Q1 2024

Shares 423,100 Value ($000) $58,354 Avg Close $136.57 Range $128.00 - $148.37

Q4 2023

Shares 519,279 Value ($000) $68,420 Avg Close $115.11 Range $103.63 - $133.64

Q3 2023

Shares 415,900 Value ($000) $46,789 Avg Close $105.30 Range $93.28 - $119.29

Q2 2023

Shares 489,000 Value ($000) $46,113 Avg Close $97.71 Range $89.04 - $107.98

Q1 2023

Shares 489,000 Value ($000) $49,497 Avg Close $104.06 Range $92.89 - $125.02

Q4 2022

Shares 687,700 Value ($000) $82,139 Avg Close $117.13 Range $105.14 - $129.29

Q3 2022

Shares 896,545 Value ($000) $95,222 Avg Close $101.46 Range $91.53 - $109.26

Q2 2022

Shares 849,545 Value ($000) $82,814 Avg Close $92.29 Range $75.25 - $100.73

Q1 2022

Shares 875,515 Value ($000) $82,080 Avg Close $84.75 Range $71.88 - $95.87

Q4 2021

Shares 931,915 Value ($000) $79,371 Avg Close $91.99 Range $78.31 - $108.02

Q3 2021

Shares 1,192,015 Value ($000) $114,326 Avg Close $94.46 Range $84.77 - $101.43

Q2 2021

Shares 1,231,115 Value ($000) $119,812 Avg Close $95.85 Range $87.19 - $103.72

Q1 2021

Shares 1,301,715 Value ($000) $126,592 Avg Close $104.86 Range $87.37 - $120.27

Q4 2020

Shares 1,301,715 Value ($000) $124,769 Avg Close $96.59 Range $86.02 - $108.93

Q3 2020

Shares 1,301,715 Value ($000) $125,173 Avg Close $115.68 Range $95.42 - $136.26

Q2 2020

Shares 1,185,915 Value ($000) $144,682 Avg Close $110.51 Range $82.51 - $131.00

Q1 2020

Shares 1,155,015 Value ($000) $99,967 Avg Close $97.87 Range $72.14 - $115.24

Q4 2019

Shares 935,970 Value ($000) $100,607 Avg Close $104.70 Range $84.68 - $119.65

Q3 2019

Shares 1,575,170 Value ($000) $141,939 Avg Close $93.43 Range $83.19 - $102.51

Q2 2019

Shares 1,833,200 Value ($000) $154,777 Avg Close $82.11 Range $71.85 - $91.98

Q1 2019

Shares 1,833,200 Value ($000) $161,505 Avg Close $83.58 Range $67.10 - $92.71

Q4 2018

Shares 494,200 Value ($000) $35,291 Avg Close $95.81 Range $64.72 - $125.59

Q3 2018

Shares 137,800 Value ($000) $16,943 Avg Close $113.46 Range $96.98 - $126.98

Q2 2018

Shares 137,800 Value ($000) $13,537 Avg Close $89.51 Range $74.34 - $106.26

Q1 2018

Shares 75,000 Value ($000) $6,220 Avg Close $84.45 Range $74.12 - $92.98

Q3 2017

Shares 284,841 Value ($000) $17,455 Avg Close $52.77 Range $44.75 - $61.51

Q2 2017

Shares 284,841 Value ($000) $13,103 Avg Close $48.51 Range $39.21 - $55.38

Q1 2017

Shares 441,341 Value ($000) $19,110 Avg Close $42.84 Range $38.38 - $47.43

Q4 2016

Shares 2,128,774 Value ($000) $82,384 Avg Close $45.27 Range $37.35 - $54.91

Q3 2016

Shares 1,815,474 Value ($000) $91,936 Avg Close $49.80 Range $44.69 - $55.15

Q2 2016

Shares 1,815,474 Value ($000) $82,513 Avg Close $46.04 Range $39.01 - $53.00

Q1 2016

Shares 2,653,874 Value ($000) $104,961 Avg Close $39.68 Range $31.25 - $55.94

Q4 2015

Shares 2,514,974 Value ($000) $142,272 Avg Close $50.83 Range $37.76 - $58.46

Q3 2015

Shares 3,816,050 Value ($000) $151,841 Avg Close $48.33 Range $33.61 - $56.97

Q2 2015

Shares 5,094,500 Value ($000) $243,313 Avg Close $42.40 Range $32.67 - $49.49

Q1 2015

Shares 5,833,600 Value ($000) $231,652 Avg Close $35.77 Range $19.68 - $45.36

Q4 2014

Shares 5,968,600 Value ($000) $133,339 Avg Close $18.95 Range $15.20 - $24.86

Q3 2014

Shares 5,793,600 Value ($000) $90,786 Avg Close $14.95 Range $12.63 - $17.00

Q2 2014

Shares 4,675,700 Value ($000) $69,364 Avg Close $14.11 Range $12.17 - $16.47

Q1 2014

Shares 5,451,000 Value ($000) $87,761 Avg Close $17.10 Range $9.19 - $20.29

Q4 2013

Shares 2,631,000 Value ($000) $24,574 Avg Close $9.76 Range $8.57 - $11.88

Q3 2013

Shares 575,000 Value ($000) $6,509 Avg Close $13.75 Range $10.42 - $16.74

Q2 2013

Shares 768,000 Value ($000) $10,276 Avg Close $12.28 Range $10.87 - $14.06

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	314,240	$44,569	$144.87	$133.61 - $160.18
Q3 2025	353,640	$49,644	$135.50	$123.67 - $148.00
Q2 2025	438,540	$55,120	$114.68	$84.23 - $130.46
Q1 2025	934,640	$103,371	$126.68	$105.18 - $154.61
Q4 2024	938,120	$128,053	$123.68	$110.95 - $140.00
Q3 2024	302,220	$34,822	$137.09	$114.08 - $157.98
Q2 2024	448,200	$61,704	$137.14	$129.33 - $145.78
Q1 2024	423,100	$58,354	$136.57	$128.00 - $148.37
Q4 2023	519,279	$68,420	$115.11	$103.63 - $133.64
Q3 2023	415,900	$46,789	$105.30	$93.28 - $119.29
Q2 2023	489,000	$46,113	$97.71	$89.04 - $107.98
Q1 2023	489,000	$49,497	$104.06	$92.89 - $125.02
Q4 2022	687,700	$82,139	$117.13	$105.14 - $129.29
Q3 2022	896,545	$95,222	$101.46	$91.53 - $109.26
Q2 2022	849,545	$82,814	$92.29	$75.25 - $100.73
Q1 2022	875,515	$82,080	$84.75	$71.88 - $95.87
Q4 2021	931,915	$79,371	$91.99	$78.31 - $108.02
Q3 2021	1,192,015	$114,326	$94.46	$84.77 - $101.43
Q2 2021	1,231,115	$119,812	$95.85	$87.19 - $103.72
Q1 2021	1,301,715	$126,592	$104.86	$87.37 - $120.27
Q4 2020	1,301,715	$124,769	$96.59	$86.02 - $108.93
Q3 2020	1,301,715	$125,173	$115.68	$95.42 - $136.26
Q2 2020	1,185,915	$144,682	$110.51	$82.51 - $131.00
Q1 2020	1,155,015	$99,967	$97.87	$72.14 - $115.24
Q4 2019	935,970	$100,607	$104.70	$84.68 - $119.65
Q3 2019	1,575,170	$141,939	$93.43	$83.19 - $102.51
Q2 2019	1,833,200	$154,777	$82.11	$71.85 - $91.98
Q1 2019	1,833,200	$161,505	$83.58	$67.10 - $92.71
Q4 2018	494,200	$35,291	$95.81	$64.72 - $125.59
Q3 2018	137,800	$16,943	$113.46	$96.98 - $126.98
Q2 2018	137,800	$13,537	$89.51	$74.34 - $106.26
Q1 2018	75,000	$6,220	$84.45	$74.12 - $92.98
Q3 2017	284,841	$17,455	$52.77	$44.75 - $61.51
Q2 2017	284,841	$13,103	$48.51	$39.21 - $55.38
Q1 2017	441,341	$19,110	$42.84	$38.38 - $47.43
Q4 2016	2,128,774	$82,384	$45.27	$37.35 - $54.91
Q3 2016	1,815,474	$91,936	$49.80	$44.69 - $55.15
Q2 2016	1,815,474	$82,513	$46.04	$39.01 - $53.00
Q1 2016	2,653,874	$104,961	$39.68	$31.25 - $55.94
Q4 2015	2,514,974	$142,272	$50.83	$37.76 - $58.46
Q3 2015	3,816,050	$151,841	$48.33	$33.61 - $56.97
Q2 2015	5,094,500	$243,313	$42.40	$32.67 - $49.49
Q1 2015	5,833,600	$231,652	$35.77	$19.68 - $45.36
Q4 2014	5,968,600	$133,339	$18.95	$15.20 - $24.86
Q3 2014	5,793,600	$90,786	$14.95	$12.63 - $17.00
Q2 2014	4,675,700	$69,364	$14.11	$12.17 - $16.47
Q1 2014	5,451,000	$87,761	$17.10	$9.19 - $20.29
Q4 2013	2,631,000	$24,574	$9.76	$8.57 - $11.88
Q3 2013	575,000	$6,509	$13.75	$10.42 - $16.74
Q2 2013	768,000	$10,276	$12.28	$10.87 - $14.06