OPKO HEALTH INC

Ticker: OPK CUSIP: 68375N103 Class: COM

ROYAL BANK OF CANADA's Holding History (CIK: 0001000275)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 261,020 Value ($000) $329 Avg Close $1.39 Range $1.22 - $1.60

Q3 2025

Shares 272,866 Value ($000) $423 Avg Close $1.37 Range $1.11 - $1.55

Q2 2025

Shares 267,448 Value ($000) $352 Avg Close $1.37 Range $1.21 - $1.69

Q1 2025

Shares 236,609 Value ($000) $393 Avg Close $1.65 Range $1.43 - $2.04

Q4 2024

Shares 241,928 Value ($000) $356 Avg Close $1.53 Range $1.37 - $1.76

Q3 2024

Shares 222,055 Value ($000) $332 Avg Close $1.48 Range $1.19 - $1.75

Q2 2024

Shares 223,173 Value ($000) $279 Avg Close $1.30 Range $1.15 - $1.45

Q1 2024

Shares 262,507 Value ($000) $314 Avg Close $1.00 Range $0.85 - $1.57

Q4 2023

Shares 304,411 Value ($000) $460 Avg Close $1.45 Range $1.20 - $1.66

Q3 2023

Shares 254,163 Value ($000) $406 Avg Close $1.82 Range $1.48 - $2.24

Q2 2023

Shares 228,425 Value ($000) $495 Avg Close $1.56 Range $1.34 - $2.24

Q1 2023

Shares 209,067 Value ($000) $305 Avg Close $1.29 Range $1.00 - $1.68

Q4 2022

Shares 313,355 Value ($000) $392 Avg Close $1.58 Range $1.03 - $2.01

Q3 2022

Shares 246,922 Value ($000) $466 Avg Close $2.36 Range $1.78 - $2.86

Q2 2022

Shares 190,216 Value ($000) $482 Avg Close $2.92 Range $2.17 - $3.63

Q1 2022

Shares 214,989 Value ($000) $740 Avg Close $3.53 Range $2.79 - $4.96

Q4 2021

Shares 291,805 Value ($000) $1,404 Avg Close $4.05 Range $3.49 - $5.25

Q3 2021

Shares 144,699 Value ($000) $528 Avg Close $3.72 Range $3.26 - $4.24

Q2 2021

Shares 112,932 Value ($000) $457 Avg Close $3.92 Range $3.32 - $4.63

Q1 2021

Shares 147,944 Value ($000) $635 Avg Close $4.78 Range $3.83 - $6.27

Q4 2020

Shares 127,290 Value ($000) $502 Avg Close $4.18 Range $3.02 - $4.92

Q3 2020

Shares 114,690 Value ($000) $423 Avg Close $4.22 Range $2.84 - $6.47

Q2 2020

Shares 128,102 Value ($000) $437 Avg Close $2.24 Range $1.12 - $3.52

Q1 2020

Shares 207,763 Value ($000) $277 Avg Close $1.57 Range $1.30 - $2.91

Q4 2019

Shares 181,923 Value ($000) $268 Avg Close $1.67 Range $1.33 - $2.43

Q3 2019

Shares 99,132 Value ($000) $207 Avg Close $2.04 Range $1.75 - $2.53

Q2 2019

Shares 98,432 Value ($000) $241 Avg Close $2.18 Range $1.73 - $2.64

Q1 2019

Shares 98,209 Value ($000) $256 Avg Close $3.03 Range $2.40 - $3.94

Q4 2018

Shares 195,967 Value ($000) $589 Avg Close $3.39 Range $2.34 - $3.92

Q3 2018

Shares 193,583 Value ($000) $670 Avg Close $5.26 Range $3.21 - $6.40

Q2 2018

Shares 88,528 Value ($000) $416 Avg Close $3.79 Range $2.91 - $5.02

Q1 2018

Shares 86,822 Value ($000) $275 Avg Close $4.03 Range $2.66 - $5.14

Q4 2017

Shares 118,650 Value ($000) $581 Avg Close $5.80 Range $4.50 - $7.08

Q3 2017

Shares 108,229 Value ($000) $742 Avg Close $6.31 Range $5.85 - $7.24

Q2 2017

Shares 118,749 Value ($000) $781 Avg Close $7.01 Range $5.99 - $8.04

Q1 2017

Shares 115,010 Value ($000) $920 Avg Close $8.42 Range $7.13 - $9.55

Q4 2016

Shares 183,176 Value ($000) $1,704 Avg Close $10.35 Range $8.92 - $12.15

Q3 2016

Shares 164,144 Value ($000) $1,738 Avg Close $9.96 Range $8.91 - $11.31

Q2 2016

Shares 171,765 Value ($000) $1,605 Avg Close $10.16 Range $8.71 - $11.39

Q1 2016

Shares 268,097 Value ($000) $2,786 Avg Close $9.14 Range $7.12 - $11.85

Q4 2015

Shares 477,691 Value ($000) $4,800 Avg Close $10.02 Range $8.20 - $11.49

Q3 2015

Shares 638,730 Value ($000) $5,371 Avg Close $13.24 Range $8.23 - $17.51

Q2 2015

Shares 181,915 Value ($000) $2,925 Avg Close $15.55 Range $13.71 - $19.20

Q1 2015

Shares 138,365 Value ($000) $1,961 Avg Close $13.01 Range $9.81 - $15.23

Q4 2014

Shares 164,279 Value ($000) $1,642 Avg Close $8.56 Range $8.02 - $10.16

Q3 2014

Shares 134,435 Value ($000) $1,143 Avg Close $8.79 Range $8.09 - $9.62

Q2 2014

Shares 114,601 Value ($000) $1,013 Avg Close $8.73 Range $7.82 - $9.83

Q1 2014

Shares 109,101 Value ($000) $1,017 Avg Close $8.77 Range $7.32 - $10.25

Q4 2013

Shares 118,251 Value ($000) $998 Avg Close $10.11 Range $8.17 - $12.95

Q3 2013

Shares 116,701 Value ($000) $1,028 Avg Close $8.02 Range $7.13 - $10.00

Q2 2013

Shares 123,601 Value ($000) $878 Avg Close $6.91 Range $6.14 - $7.65

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	261,020	$329	$1.39	$1.22 - $1.60
Q3 2025	272,866	$423	$1.37	$1.11 - $1.55
Q2 2025	267,448	$352	$1.37	$1.21 - $1.69
Q1 2025	236,609	$393	$1.65	$1.43 - $2.04
Q4 2024	241,928	$356	$1.53	$1.37 - $1.76
Q3 2024	222,055	$332	$1.48	$1.19 - $1.75
Q2 2024	223,173	$279	$1.30	$1.15 - $1.45
Q1 2024	262,507	$314	$1.00	$0.85 - $1.57
Q4 2023	304,411	$460	$1.45	$1.20 - $1.66
Q3 2023	254,163	$406	$1.82	$1.48 - $2.24
Q2 2023	228,425	$495	$1.56	$1.34 - $2.24
Q1 2023	209,067	$305	$1.29	$1.00 - $1.68
Q4 2022	313,355	$392	$1.58	$1.03 - $2.01
Q3 2022	246,922	$466	$2.36	$1.78 - $2.86
Q2 2022	190,216	$482	$2.92	$2.17 - $3.63
Q1 2022	214,989	$740	$3.53	$2.79 - $4.96
Q4 2021	291,805	$1,404	$4.05	$3.49 - $5.25
Q3 2021	144,699	$528	$3.72	$3.26 - $4.24
Q2 2021	112,932	$457	$3.92	$3.32 - $4.63
Q1 2021	147,944	$635	$4.78	$3.83 - $6.27
Q4 2020	127,290	$502	$4.18	$3.02 - $4.92
Q3 2020	114,690	$423	$4.22	$2.84 - $6.47
Q2 2020	128,102	$437	$2.24	$1.12 - $3.52
Q1 2020	207,763	$277	$1.57	$1.30 - $2.91
Q4 2019	181,923	$268	$1.67	$1.33 - $2.43
Q3 2019	99,132	$207	$2.04	$1.75 - $2.53
Q2 2019	98,432	$241	$2.18	$1.73 - $2.64
Q1 2019	98,209	$256	$3.03	$2.40 - $3.94
Q4 2018	195,967	$589	$3.39	$2.34 - $3.92
Q3 2018	193,583	$670	$5.26	$3.21 - $6.40
Q2 2018	88,528	$416	$3.79	$2.91 - $5.02
Q1 2018	86,822	$275	$4.03	$2.66 - $5.14
Q4 2017	118,650	$581	$5.80	$4.50 - $7.08
Q3 2017	108,229	$742	$6.31	$5.85 - $7.24
Q2 2017	118,749	$781	$7.01	$5.99 - $8.04
Q1 2017	115,010	$920	$8.42	$7.13 - $9.55
Q4 2016	183,176	$1,704	$10.35	$8.92 - $12.15
Q3 2016	164,144	$1,738	$9.96	$8.91 - $11.31
Q2 2016	171,765	$1,605	$10.16	$8.71 - $11.39
Q1 2016	268,097	$2,786	$9.14	$7.12 - $11.85
Q4 2015	477,691	$4,800	$10.02	$8.20 - $11.49
Q3 2015	638,730	$5,371	$13.24	$8.23 - $17.51
Q2 2015	181,915	$2,925	$15.55	$13.71 - $19.20
Q1 2015	138,365	$1,961	$13.01	$9.81 - $15.23
Q4 2014	164,279	$1,642	$8.56	$8.02 - $10.16
Q3 2014	134,435	$1,143	$8.79	$8.09 - $9.62
Q2 2014	114,601	$1,013	$8.73	$7.82 - $9.83
Q1 2014	109,101	$1,017	$8.77	$7.32 - $10.25
Q4 2013	118,251	$998	$10.11	$8.17 - $12.95
Q3 2013	116,701	$1,028	$8.02	$7.13 - $10.00
Q2 2013	123,601	$878	$6.91	$6.14 - $7.65