ORCHESTRA BIOMED HLDGS INC

Ticker: OBIO CUSIP: 68572M106 Class: Common Stock

RENAISSANCE TECHNOLOGIES LLC's Holding History (CIK: 0001037389)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 151,300 Value ($000) $628 Avg Close $4.03 Range $2.42 - $5.42

Q3 2025

Shares 380,508 Value ($000) $944 Avg Close $2.76 Range $2.20 - $3.53

Q2 2025

Shares 169,400 Value ($000) $454 Avg Close $2.92 Range $2.37 - $4.06

Q2 2023

Shares 12,600 Value ($000) $0 Avg Close $15.17 Range $6.30 - $23.39

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	151,300	$628	$4.03	$2.42 - $5.42
Q3 2025	380,508	$944	$2.76	$2.20 - $3.53
Q2 2025	169,400	$454	$2.92	$2.37 - $4.06
Q2 2023	12,600	$0	$15.17	$6.30 - $23.39