PRAXIS PRECISION MEDICINES I

Ticker: PRAX CUSIP: 74006W207 Class: Common Stock

NORTHERN TRUST CORP's Holding History (CIK: 0000073124)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 192,284 Value ($000) $56,674 Avg Close $186.22 Range $50.31 - $317.72

Q3 2025

Shares 168,353 Value ($000) $8,923 Avg Close $48.49 Range $37.19 - $61.03

Q2 2025

Shares 213,712 Value ($000) $8,987 Avg Close $38.08 Range $26.70 - $46.93

Q1 2025

Shares 165,183 Value ($000) $6,255 Avg Close $62.45 Range $30.01 - $91.83

Q4 2024

Shares 167,590 Value ($000) $12,898 Avg Close $72.36 Range $55.33 - $86.93

Q3 2024

Shares 152,267 Value ($000) $8,761 Avg Close $54.02 Range $38.99 - $63.93

Q2 2024

Shares 48,069 Value ($000) $1,988 Avg Close $47.26 Range $33.01 - $63.00

Q1 2024

Shares 27,279 Value ($000) $1,665 Avg Close $44.86 Range $20.50 - $67.21

Q4 2023

Shares 19,364 Value ($000) $431 Avg Close $18.01 Range $13.01 - $27.60

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	192,284	$56,674	$186.22	$50.31 - $317.72
Q3 2025	168,353	$8,923	$48.49	$37.19 - $61.03
Q2 2025	213,712	$8,987	$38.08	$26.70 - $46.93
Q1 2025	165,183	$6,255	$62.45	$30.01 - $91.83
Q4 2024	167,590	$12,898	$72.36	$55.33 - $86.93
Q3 2024	152,267	$8,761	$54.02	$38.99 - $63.93
Q2 2024	48,069	$1,988	$47.26	$33.01 - $63.00
Q1 2024	27,279	$1,665	$44.86	$20.50 - $67.21
Q4 2023	19,364	$431	$18.01	$13.01 - $27.60