PRAXIS PRECISION MEDICINES I

Ticker: PRAX CUSIP: 74006W207 Class: Common Stock

GROUP ONE TRADING, L.P.'s Holding History (CIK: 0000932540)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 5,539 Value ($000) $1,633 Avg Close $186.22 Range $50.31 - $317.72

Q3 2025

Shares 16,628 Value ($000) $881 Avg Close $48.49 Range $37.19 - $61.03

Q1 2025

Shares 10,927 Value ($000) $414 Avg Close $62.45 Range $30.01 - $91.83

Q3 2024

Shares 60,818 Value ($000) $3,499 Avg Close $54.02 Range $38.99 - $63.93

Q1 2024

Shares 13,522 Value ($000) $825 Avg Close $44.86 Range $20.50 - $67.21

Q4 2023

Shares 160 Value ($000) $4 Avg Close $18.01 Range $13.01 - $27.60

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	5,539	$1,633	$186.22	$50.31 - $317.72
Q3 2025	16,628	$881	$48.49	$37.19 - $61.03
Q1 2025	10,927	$414	$62.45	$30.01 - $91.83
Q3 2024	60,818	$3,499	$54.02	$38.99 - $63.93
Q1 2024	13,522	$825	$44.86	$20.50 - $67.21
Q4 2023	160	$4	$18.01	$13.01 - $27.60