PRAXIS PRECISION MEDICINES I

Ticker: PRAX CUSIP: 74006W207 Class: Common Stock

ORBIMED ADVISORS LLC's Holding History (CIK: 0001055951)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 94,500 Value ($000) $27,853 Avg Close $186.22 Range $50.31 - $317.72

Q1 2024

Shares 460,512 Value ($000) $28,100 Avg Close $44.86 Range $20.50 - $67.21

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	94,500	$27,853	$186.22	$50.31 - $317.72
Q1 2024	460,512	$28,100	$44.86	$20.50 - $67.21