PRAXIS PRECISION MEDICINES I

Ticker: PRAX CUSIP: 74006W207 Class: Common Stock

Squarepoint Ops LLC's Holding History (CIK: 0001642575)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 1,890 Value ($000) $557 Avg Close $186.22 Range $50.31 - $317.72

Q4 2024

Shares 7,782 Value ($000) $599 Avg Close $72.36 Range $55.33 - $86.93

Q3 2024

Shares 14,658 Value ($000) $843 Avg Close $54.02 Range $38.99 - $63.93

Q2 2024

Shares 13,348 Value ($000) $552 Avg Close $47.26 Range $33.01 - $63.00

Q1 2024

Shares 6,406 Value ($000) $391 Avg Close $44.86 Range $20.50 - $67.21

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	1,890	$557	$186.22	$50.31 - $317.72
Q4 2024	7,782	$599	$72.36	$55.33 - $86.93
Q3 2024	14,658	$843	$54.02	$38.99 - $63.93
Q2 2024	13,348	$552	$47.26	$33.01 - $63.00
Q1 2024	6,406	$391	$44.86	$20.50 - $67.21