PRELUDE THERAPEUTICS INC

Ticker: PRLD CUSIP: 74065P101 Class: Common Stock

Rock Springs Capital Management LP's Holding History (CIK: 0001595725)

Note: Option positions (PUT/CALL) are excluded.

Q2 2022

Shares 368,959 Value ($000) $1,926 Avg Close $5.09 Range $3.87 - $7.96

Q1 2022

Shares 368,959 Value ($000) $2,546 Avg Close $9.15 Range $6.76 - $13.40

Q4 2021

Shares 368,959 Value ($000) $4,594 Avg Close $16.27 Range $10.96 - $32.77

Q3 2021

Shares 362,359 Value ($000) $11,324 Avg Close $32.38 Range $24.72 - $43.55

Q2 2021

Shares 382,359 Value ($000) $10,947 Avg Close $35.61 Range $28.26 - $45.42

Q1 2021

Shares 378,195 Value ($000) $16,387 Avg Close $66.34 Range $37.01 - $95.38

Q4 2020

Shares 360,363 Value ($000) $25,784 Avg Close $49.73 Range $27.53 - $89.06

Q3 2020

Shares 360,263 Value ($000) $10,855 Avg Close $28.24 Range $23.69 - $31.44

Period	Shares	Value ($000)	Average Close	Price Range
Q2 2022	368,959	$1,926	$5.09	$3.87 - $7.96
Q1 2022	368,959	$2,546	$9.15	$6.76 - $13.40
Q4 2021	368,959	$4,594	$16.27	$10.96 - $32.77
Q3 2021	362,359	$11,324	$32.38	$24.72 - $43.55
Q2 2021	382,359	$10,947	$35.61	$28.26 - $45.42
Q1 2021	378,195	$16,387	$66.34	$37.01 - $95.38
Q4 2020	360,363	$25,784	$49.73	$27.53 - $89.06
Q3 2020	360,263	$10,855	$28.24	$23.69 - $31.44