PROTAGONIST THERAPEUTICS INC

Ticker: PTGX CUSIP: 74366E102 Class: Common Stock

Novo Holdings A/S's Holding History (CIK: 0001388325)

Note: Option positions (PUT/CALL) are excluded.

Q2 2021

Shares 600,010 Value ($000) $26,928 Avg Close $33.01 Range $24.14 - $45.93

Q1 2021

Shares 867,724 Value ($000) $22,474 Avg Close $25.31 Range $18.82 - $32.10

Q4 2020

Shares 867,724 Value ($000) $17,493 Avg Close $21.52 Range $17.44 - $25.65

Q3 2020

Shares 794,369 Value ($000) $15,530 Avg Close $18.76 Range $14.16 - $23.25

Q2 2020

Shares 824,169 Value ($000) $14,555 Avg Close $12.55 Range $6.00 - $19.67

Q1 2020

Shares 697,899 Value ($000) $4,927 Avg Close $7.49 Range $5.30 - $9.30

Q4 2019

Shares 479,074 Value ($000) $3,377 Avg Close $9.93 Range $4.47 - $13.77

Q3 2019

Shares 479,074 Value ($000) $5,754 Avg Close $12.60 Range $8.26 - $16.67

Q2 2019

Shares 23,901 Value ($000) $289 Avg Close $11.06 Range $8.88 - $13.14

Period	Shares	Value ($000)	Average Close	Price Range
Q2 2021	600,010	$26,928	$33.01	$24.14 - $45.93
Q1 2021	867,724	$22,474	$25.31	$18.82 - $32.10
Q4 2020	867,724	$17,493	$21.52	$17.44 - $25.65
Q3 2020	794,369	$15,530	$18.76	$14.16 - $23.25
Q2 2020	824,169	$14,555	$12.55	$6.00 - $19.67
Q1 2020	697,899	$4,927	$7.49	$5.30 - $9.30
Q4 2019	479,074	$3,377	$9.93	$4.47 - $13.77
Q3 2019	479,074	$5,754	$12.60	$8.26 - $16.67
Q2 2019	23,901	$289	$11.06	$8.88 - $13.14