PUMA BIOTECHNOLOGY INC

Ticker: PBYI CUSIP: 74587V107 Class: Common Stock

Opaleye Management Inc.'s Holding History (CIK: 0001595855)

Note: Option positions (PUT/CALL) are excluded.

Q4 2018

Shares 100,000 Value ($000) $2,035 Avg Close $30.01 Range $17.60 - $47.14

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2018	100,000	$2,035	$30.01	$17.60 - $47.14