RAPPORT THERAPEUTICS INC

Ticker: RAPP CUSIP: 75383L102 Class: Common Stock

Siren, L.L.C.'s Holding History (CIK: 0002005245)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 708,469 Value ($000) $21,495 Avg Close $27.68 Range $23.75 - $32.36

Q3 2025

Shares 1,053,469 Value ($000) $31,288 Avg Close $17.84 Range $11.05 - $42.27

Q2 2025

Shares 378,469 Value ($000) $4,303 Avg Close $10.61 Range $7.73 - $14.79

Q1 2025

Shares 378,469 Value ($000) $3,796 Avg Close $12.98 Range $6.43 - $19.75

Q4 2024

Shares 384,197 Value ($000) $6,816 Avg Close $22.16 Range $17.01 - $29.74

Q3 2024

Shares 384,197 Value ($000) $7,868 Avg Close $21.49 Range $16.55 - $28.08

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	708,469	$21,495	$27.68	$23.75 - $32.36
Q3 2025	1,053,469	$31,288	$17.84	$11.05 - $42.27
Q2 2025	378,469	$4,303	$10.61	$7.73 - $14.79
Q1 2025	378,469	$3,796	$12.98	$6.43 - $19.75
Q4 2024	384,197	$6,816	$22.16	$17.01 - $29.74
Q3 2024	384,197	$7,868	$21.49	$16.55 - $28.08