RHYTHM PHARMACEUTICALS INC

Ticker: RYTM CUSIP: 76243J105 Class: Common Stock

RHUMBLINE ADVISERS's Holding History (CIK: 0001115418)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 71,212 Value ($000) $7,623 Avg Close $106.08 Range $95.27 - $122.20

Q3 2025

Shares 82,068 Value ($000) $8,288 Avg Close $92.84 Range $62.84 - $106.52

Q2 2025

Shares 87,526 Value ($000) $5,531 Avg Close $61.23 Range $45.91 - $69.89

Q1 2025

Shares 85,719 Value ($000) $4,541 Avg Close $55.48 Range $47.86 - $62.14

Q4 2024

Shares 82,731 Value ($000) $4,631 Avg Close $55.24 Range $46.80 - $68.58

Q3 2024

Shares 80,714 Value ($000) $4,229 Avg Close $47.92 Range $40.46 - $55.64

Q2 2024

Shares 83,063 Value ($000) $3,411 Avg Close $39.92 Range $35.17 - $45.92

Q1 2024

Shares 76,724 Value ($000) $3,324 Avg Close $43.76 Range $37.66 - $52.57

Q4 2023

Shares 73,172 Value ($000) $3,364 Avg Close $31.55 Range $20.97 - $50.27

Q3 2023

Shares 73,459 Value ($000) $1,684 Avg Close $22.39 Range $15.50 - $28.25

Q2 2023

Shares 69,598 Value ($000) $1,148 Avg Close $18.05 Range $15.52 - $21.67

Q1 2022

Shares 56,942 Value ($000) $656 Avg Close $8.78 Range $6.01 - $12.61

Q4 2021

Shares 60,537 Value ($000) $604 Avg Close $11.23 Range $8.44 - $14.21

Q3 2021

Shares 61,287 Value ($000) $800 Avg Close $15.27 Range $11.53 - $20.81

Q2 2021

Shares 61,012 Value ($000) $1,195 Avg Close $20.76 Range $18.19 - $23.35

Q1 2021

Shares 40,155 Value ($000) $854 Avg Close $29.00 Range $19.13 - $43.26

Q4 2020

Shares 41,578 Value ($000) $1,236 Avg Close $25.42 Range $20.49 - $34.27

Q3 2020

Shares 38,713 Value ($000) $839 Avg Close $22.93 Range $18.00 - $32.24

Q2 2020

Shares 44,628 Value ($000) $995 Avg Close $19.49 Range $14.12 - $25.86

Q1 2020

Shares 34,504 Value ($000) $525 Avg Close $17.90 Range $12.99 - $23.14

Q4 2019

Shares 32,395 Value ($000) $744 Avg Close $22.21 Range $19.06 - $25.84

Q3 2019

Shares 25,853 Value ($000) $558 Avg Close $21.45 Range $18.00 - $25.04

Q2 2019

Shares 26,093 Value ($000) $574 Avg Close $25.25 Range $20.64 - $29.13

Q1 2019

Shares 19,603 Value ($000) $537 Avg Close $28.74 Range $24.76 - $31.94

Q4 2018

Shares 19,553 Value ($000) $526 Avg Close $27.64 Range $23.44 - $32.00

Q3 2018

Shares 12,095 Value ($000) $353 Avg Close $31.60 Range $26.86 - $36.40

Q2 2018

Shares 11,434 Value ($000) $357 Avg Close $27.34 Range $16.80 - $37.23

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	71,212	$7,623	$106.08	$95.27 - $122.20
Q3 2025	82,068	$8,288	$92.84	$62.84 - $106.52
Q2 2025	87,526	$5,531	$61.23	$45.91 - $69.89
Q1 2025	85,719	$4,541	$55.48	$47.86 - $62.14
Q4 2024	82,731	$4,631	$55.24	$46.80 - $68.58
Q3 2024	80,714	$4,229	$47.92	$40.46 - $55.64
Q2 2024	83,063	$3,411	$39.92	$35.17 - $45.92
Q1 2024	76,724	$3,324	$43.76	$37.66 - $52.57
Q4 2023	73,172	$3,364	$31.55	$20.97 - $50.27
Q3 2023	73,459	$1,684	$22.39	$15.50 - $28.25
Q2 2023	69,598	$1,148	$18.05	$15.52 - $21.67
Q1 2022	56,942	$656	$8.78	$6.01 - $12.61
Q4 2021	60,537	$604	$11.23	$8.44 - $14.21
Q3 2021	61,287	$800	$15.27	$11.53 - $20.81
Q2 2021	61,012	$1,195	$20.76	$18.19 - $23.35
Q1 2021	40,155	$854	$29.00	$19.13 - $43.26
Q4 2020	41,578	$1,236	$25.42	$20.49 - $34.27
Q3 2020	38,713	$839	$22.93	$18.00 - $32.24
Q2 2020	44,628	$995	$19.49	$14.12 - $25.86
Q1 2020	34,504	$525	$17.90	$12.99 - $23.14
Q4 2019	32,395	$744	$22.21	$19.06 - $25.84
Q3 2019	25,853	$558	$21.45	$18.00 - $25.04
Q2 2019	26,093	$574	$25.25	$20.64 - $29.13
Q1 2019	19,603	$537	$28.74	$24.76 - $31.94
Q4 2018	19,553	$526	$27.64	$23.44 - $32.00
Q3 2018	12,095	$353	$31.60	$26.86 - $36.40
Q2 2018	11,434	$357	$27.34	$16.80 - $37.23