RHYTHM PHARMACEUTICALS INC

Ticker: RYTM CUSIP: 76243J105 Class: Common Stock

EcoR1 Capital, LLC's Holding History (CIK: 0001587114)

Note: Option positions (PUT/CALL) are excluded.

Q2 2019

Shares 223,167 Value ($000) $4,910 Avg Close $25.25 Range $20.64 - $29.13

Q1 2019

Shares 400,838 Value ($000) $10,987 Avg Close $28.74 Range $24.76 - $31.94

Q4 2018

Shares 400,838 Value ($000) $10,775 Avg Close $27.64 Range $23.44 - $32.00

Q1 2018

Shares 318,564 Value ($000) $6,339 Avg Close $26.55 Range $19.25 - $32.35

Q4 2017

Shares 530,161 Value ($000) $15,406 Avg Close $26.40 Range $21.38 - $31.63

Period	Shares	Value ($000)	Average Close	Price Range
Q2 2019	223,167	$4,910	$25.25	$20.64 - $29.13
Q1 2019	400,838	$10,987	$28.74	$24.76 - $31.94
Q4 2018	400,838	$10,775	$27.64	$23.44 - $32.00
Q1 2018	318,564	$6,339	$26.55	$19.25 - $32.35
Q4 2017	530,161	$15,406	$26.40	$21.38 - $31.63