SILENCE THERAPEUTICS PLC

Ticker: SLN CUSIP: 82686Q101 Class: ADR

Frazier Life Sciences Management, L.P.'s Holding History (CIK: 0001892134)

Note: Option positions (PUT/CALL) are excluded.

Q3 2025
Shares 970,130 Value ($000) $5,035 Avg Close — Range —
Q2 2025
Shares 970,130 Value ($000) $5,627 Avg Close — Range —
Q1 2025
Shares 1,148,591 Value ($000) $3,239 Avg Close — Range —
Q4 2024
Shares 1,148,591 Value ($000) $7,902 Avg Close — Range —
Q3 2024
Shares 1,148,591 Value ($000) $20,881 Avg Close — Range —
Q2 2024
Shares 1,148,591 Value ($000) $21,823 Avg Close — Range —
Q1 2024
Shares 1,148,591 Value ($000) $24,810 Avg Close — Range —
Q4 2023
Shares 881,173 Value ($000) $15,306 Avg Close — Range —
Q3 2023
Shares 881,173 Value ($000) $8,662 Avg Close — Range —
Q2 2023
Shares 881,173 Value ($000) $4,846 Avg Close — Range —
Q1 2023
Shares 881,173 Value ($000) $5,463 Avg Close — Range —
Q4 2022
Shares 881,173 Value ($000) $13,438 Avg Close — Range —
Q3 2022
Shares 881,173 Value ($000) $8,697 Avg Close — Range —
Q2 2022
Shares 881,173 Value ($000) $10,442 Avg Close — Range —
Q1 2022
Shares 881,173 Value ($000) $16,742 Avg Close — Range —