SILENCE THERAPEUTICS PLC

Ticker: SLN CUSIP: 82686Q101 Class: ADR

Siren, L.L.C.'s Holding History (CIK: 0002005245)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025
Shares 2,911,438 Value ($000) $17,702 Avg Close — Range —
Q3 2025
Shares 2,911,438 Value ($000) $15,110 Avg Close — Range —
Q2 2025
Shares 2,911,438 Value ($000) $16,886 Avg Close — Range —
Q1 2025
Shares 2,789,833 Value ($000) $7,867 Avg Close — Range —
Q4 2024
Shares 2,831,770 Value ($000) $19,483 Avg Close — Range —
Q3 2024
Shares 2,831,770 Value ($000) $51,482 Avg Close — Range —