SOLENO THERAPEUTICS INC

Ticker: SLNO CUSIP: 834203309 Class: Common Stock

SPHERA FUNDS MANAGEMENT LTD.'s Holding History (CIK: 0001496201)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 136,314 Value ($000) $6,311 Avg Close $54.83 Range $41.80 - $72.88

Q3 2025

Shares 41,606 Value ($000) $2,813 Avg Close $74.14 Range $48.91 - $90.32

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	136,314	$6,311	$54.83	$41.80 - $72.88
Q3 2025	41,606	$2,813	$74.14	$48.91 - $90.32