SOLENO THERAPEUTICS INC

Ticker: SLNO CUSIP: 834203309 Class: Common Stock

Siren, L.L.C.'s Holding History (CIK: 0002005245)

Note: Option positions (PUT/CALL) are excluded.

Q3 2025

Shares 467,342 Value ($000) $31,592 Avg Close $74.14 Range $48.91 - $90.32

Q2 2025

Shares 467,342 Value ($000) $39,154 Avg Close $74.85 Range $57.01 - $86.79

Q1 2025

Shares 727,337 Value ($000) $51,968 Avg Close $48.69 Range $41.50 - $73.97

Q4 2024

Shares 351,818 Value ($000) $15,814 Avg Close $51.81 Range $43.32 - $60.92

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2025	467,342	$31,592	$74.14	$48.91 - $90.32
Q2 2025	467,342	$39,154	$74.85	$57.01 - $86.79
Q1 2025	727,337	$51,968	$48.69	$41.50 - $73.97
Q4 2024	351,818	$15,814	$51.81	$43.32 - $60.92