SPERO THERAPEUTICS INC

Ticker: SPRO CUSIP: 84833T103 Class: COM

Rafferty Asset Management, LLC's Holding History (CIK: 0001389426)

Note: Option positions (PUT/CALL) are excluded.

Q4 2021

Shares 34,958 Value ($000) $560 Avg Close $15.88 Range $12.64 - $18.84

Q3 2021

Shares 18,789 Value ($000) $346 Avg Close $16.05 Range $12.75 - $19.87

Q2 2021

Shares 23,898 Value ($000) $334 Avg Close $13.97 Range $11.75 - $15.94

Q1 2021

Shares 68,963 Value ($000) $1,015 Avg Close $17.60 Range $12.70 - $22.23

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2021	34,958	$560	$15.88	$12.64 - $18.84
Q3 2021	18,789	$346	$16.05	$12.75 - $19.87
Q2 2021	23,898	$334	$13.97	$11.75 - $15.94
Q1 2021	68,963	$1,015	$17.60	$12.70 - $22.23