SPERO THERAPEUTICS INC

Ticker: SPRO CUSIP: 84833T103 Class: COM

Rock Springs Capital Management LP's Holding History (CIK: 0001595725)

Note: Option positions (PUT/CALL) are excluded.

Q3 2023

Shares 57,373 Value ($000) $69 Avg Close $1.39 Range $1.18 - $1.66

Q2 2023

Shares 669,533 Value ($000) $971 Avg Close $1.71 Range $1.39 - $2.00

Q1 2023

Shares 669,533 Value ($000) $971 Avg Close $1.67 Range $1.35 - $2.04

Q4 2022

Shares 669,533 Value ($000) $1,158 Avg Close $1.87 Range $1.46 - $2.28

Q3 2022

Shares 770,710 Value ($000) $1,541 Avg Close $0.99 Range $0.68 - $3.18

Q2 2022

Shares 770,710 Value ($000) $571 Avg Close $2.91 Range $0.73 - $7.87

Q1 2022

Shares 990,913 Value ($000) $8,621 Avg Close $10.25 Range $7.51 - $16.30

Q4 2021

Shares 945,313 Value ($000) $15,134 Avg Close $15.88 Range $12.64 - $18.84

Q3 2021

Shares 941,543 Value ($000) $17,334 Avg Close $16.05 Range $12.75 - $19.87

Q2 2021

Shares 965,928 Value ($000) $13,484 Avg Close $13.97 Range $11.75 - $15.94

Q1 2021

Shares 965,928 Value ($000) $14,218 Avg Close $17.60 Range $12.70 - $22.23

Q4 2020

Shares 1,235,000 Value ($000) $23,947 Avg Close $15.59 Range $11.03 - $23.64

Q3 2020

Shares 1,236,256 Value ($000) $13,797 Avg Close $11.83 Range $8.50 - $14.37

Q2 2020

Shares 615,177 Value ($000) $8,323 Avg Close $11.23 Range $6.88 - $14.48

Q1 2020

Shares 605,000 Value ($000) $4,888 Avg Close $8.81 Range $5.25 - $10.84

Q4 2019

Shares 525,000 Value ($000) $5,048 Avg Close $10.78 Range $8.74 - $12.46

Q3 2019

Shares 525,000 Value ($000) $5,565 Avg Close $10.54 Range $8.86 - $12.65

Q2 2019

Shares 525,000 Value ($000) $6,043 Avg Close $12.04 Range $9.91 - $14.48

Q1 2019

Shares 525,000 Value ($000) $6,725 Avg Close $10.61 Range $6.00 - $13.50

Q4 2018

Shares 525,000 Value ($000) $3,229 Avg Close $8.10 Range $5.52 - $11.40

Q3 2018

Shares 525,000 Value ($000) $5,518 Avg Close $11.61 Range $9.29 - $18.23

Q2 2018

Shares 525,000 Value ($000) $7,702 Avg Close $12.79 Range $10.12 - $19.00

Q1 2018

Shares 525,000 Value ($000) $7,481 Avg Close $12.13 Range $9.66 - $14.61

Q4 2017

Shares 525,000 Value ($000) $6,169 Avg Close $12.27 Range $9.85 - $15.40

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2023	57,373	$69	$1.39	$1.18 - $1.66
Q2 2023	669,533	$971	$1.71	$1.39 - $2.00
Q1 2023	669,533	$971	$1.67	$1.35 - $2.04
Q4 2022	669,533	$1,158	$1.87	$1.46 - $2.28
Q3 2022	770,710	$1,541	$0.99	$0.68 - $3.18
Q2 2022	770,710	$571	$2.91	$0.73 - $7.87
Q1 2022	990,913	$8,621	$10.25	$7.51 - $16.30
Q4 2021	945,313	$15,134	$15.88	$12.64 - $18.84
Q3 2021	941,543	$17,334	$16.05	$12.75 - $19.87
Q2 2021	965,928	$13,484	$13.97	$11.75 - $15.94
Q1 2021	965,928	$14,218	$17.60	$12.70 - $22.23
Q4 2020	1,235,000	$23,947	$15.59	$11.03 - $23.64
Q3 2020	1,236,256	$13,797	$11.83	$8.50 - $14.37
Q2 2020	615,177	$8,323	$11.23	$6.88 - $14.48
Q1 2020	605,000	$4,888	$8.81	$5.25 - $10.84
Q4 2019	525,000	$5,048	$10.78	$8.74 - $12.46
Q3 2019	525,000	$5,565	$10.54	$8.86 - $12.65
Q2 2019	525,000	$6,043	$12.04	$9.91 - $14.48
Q1 2019	525,000	$6,725	$10.61	$6.00 - $13.50
Q4 2018	525,000	$3,229	$8.10	$5.52 - $11.40
Q3 2018	525,000	$5,518	$11.61	$9.29 - $18.23
Q2 2018	525,000	$7,702	$12.79	$10.12 - $19.00
Q1 2018	525,000	$7,481	$12.13	$9.66 - $14.61
Q4 2017	525,000	$6,169	$12.27	$9.85 - $15.40