STOKE THERAPEUTICS INC

Ticker: STOK CUSIP: 86150R107 Class: Common Stock

SPHERA FUNDS MANAGEMENT LTD.'s Holding History (CIK: 0001496201)

Note: Option positions (PUT/CALL) are excluded.

Q4 2022

Shares 188,640 Value ($000) $1,741 Avg Close $10.40 Range $6.88 - $16.48

Q3 2022

Shares 157,200 Value ($000) $2,018 Avg Close $15.94 Range $12.15 - $22.87

Q2 2021

Shares 233,135 Value ($000) $7,847 Avg Close $35.35 Range $28.80 - $41.60

Q1 2021

Shares 150,729 Value ($000) $5,854 Avg Close $56.93 Range $35.40 - $71.58

Q1 2020

Shares 27,254 Value ($000) $624 Avg Close $24.71 Range $15.82 - $34.69

Q4 2019

Shares 256,380 Value ($000) $7,261 Avg Close $25.15 Range $19.23 - $31.86

Q3 2019

Shares 346,380 Value ($000) $7,384 Avg Close $27.89 Range $19.21 - $39.04

Q2 2019

Shares 350,944 Value ($000) $9,718 Avg Close $26.85 Range $23.38 - $31.76

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2022	188,640	$1,741	$10.40	$6.88 - $16.48
Q3 2022	157,200	$2,018	$15.94	$12.15 - $22.87
Q2 2021	233,135	$7,847	$35.35	$28.80 - $41.60
Q1 2021	150,729	$5,854	$56.93	$35.40 - $71.58
Q1 2020	27,254	$624	$24.71	$15.82 - $34.69
Q4 2019	256,380	$7,261	$25.15	$19.23 - $31.86
Q3 2019	346,380	$7,384	$27.89	$19.21 - $39.04
Q2 2019	350,944	$9,718	$26.85	$23.38 - $31.76