STOKE THERAPEUTICS INC

Ticker: STOK CUSIP: 86150R107 Class: Common Stock

Siren, L.L.C.'s Holding History (CIK: 0002005245)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 2,247,347 Value ($000) $71,331 Avg Close $30.06 Range $20.32 - $38.69

Q3 2025

Shares 2,247,347 Value ($000) $52,813 Avg Close $17.13 Range $11.19 - $24.97

Q2 2025

Shares 2,247,347 Value ($000) $25,507 Avg Close $9.49 Range $5.35 - $12.25

Q1 2025

Shares 2,247,347 Value ($000) $14,945 Avg Close $9.32 Range $6.60 - $12.98

Q4 2024

Shares 2,000,000 Value ($000) $22,060 Avg Close $12.29 Range $10.53 - $14.72

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	2,247,347	$71,331	$30.06	$20.32 - $38.69
Q3 2025	2,247,347	$52,813	$17.13	$11.19 - $24.97
Q2 2025	2,247,347	$25,507	$9.49	$5.35 - $12.25
Q1 2025	2,247,347	$14,945	$9.32	$6.60 - $12.98
Q4 2024	2,000,000	$22,060	$12.29	$10.53 - $14.72