TANGO THERAPEUTICS INC

Ticker: TNGX CUSIP: 87583X109 Class: Common Stock

Siren, L.L.C.'s Holding History (CIK: 0002005245)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 8,165,374 Value ($000) $72,345 Avg Close $8.62 Range $6.69 - $11.20

Q3 2025

Shares 5,883,188 Value ($000) $49,419 Avg Close $6.77 Range $4.80 - $8.80

Q2 2025

Shares 3,364,814 Value ($000) $17,228 Avg Close $2.47 Range $1.03 - $5.63

Q1 2025

Shares 2,565,342 Value ($000) $3,515 Avg Close $2.46 Range $1.33 - $3.65

Q4 2024

Shares 2,603,897 Value ($000) $8,046 Avg Close $4.64 Range $2.70 - $7.70

Q3 2024

Shares 2,603,897 Value ($000) $20,050 Avg Close $9.54 Range $7.20 - $12.02

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	8,165,374	$72,345	$8.62	$6.69 - $11.20
Q3 2025	5,883,188	$49,419	$6.77	$4.80 - $8.80
Q2 2025	3,364,814	$17,228	$2.47	$1.03 - $5.63
Q1 2025	2,565,342	$3,515	$2.46	$1.33 - $3.65
Q4 2024	2,603,897	$8,046	$4.64	$2.70 - $7.70
Q3 2024	2,603,897	$20,050	$9.54	$7.20 - $12.02