TAYSHA GENE THERAPIES INC

Ticker: TSHA CUSIP: 877619106 Class: Stock

Siren, L.L.C.'s Holding History (CIK: 0002005245)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 10,129,913 Value ($000) $55,715 Avg Close $4.86 Range $3.10 - $6.02

Q3 2025

Shares 11,014,737 Value ($000) $36,018 Avg Close $2.83 Range $2.25 - $3.40

Q2 2025

Shares 11,014,737 Value ($000) $25,444 Avg Close $2.17 Range $1.05 - $3.24

Q1 2025

Shares 6,514,737 Value ($000) $9,055 Avg Close $1.67 Range $1.17 - $2.07

Q4 2024

Shares 6,602,475 Value ($000) $11,422 Avg Close $2.07 Range $1.19 - $3.31

Q3 2024

Shares 4,879,875 Value ($000) $9,809 Avg Close $2.19 Range $1.93 - $2.53

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	10,129,913	$55,715	$4.86	$3.10 - $6.02
Q3 2025	11,014,737	$36,018	$2.83	$2.25 - $3.40
Q2 2025	11,014,737	$25,444	$2.17	$1.05 - $3.24
Q1 2025	6,514,737	$9,055	$1.67	$1.17 - $2.07
Q4 2024	6,602,475	$11,422	$2.07	$1.19 - $3.31
Q3 2024	4,879,875	$9,809	$2.19	$1.93 - $2.53