TECTONIC THERAPEUTIC INC

Ticker: TECX CUSIP: 878972108 Class: Common Stock

Opaleye Management Inc.'s Holding History (CIK: 0001595855)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 214,747 Value ($000) $4,480 Avg Close $18.58 Range $14.60 - $26.00

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	214,747	$4,480	$18.58	$14.60 - $26.00