TYRA BIOSCIENCES INC

Ticker: TYRA CUSIP: 90240B106 Class: Common Stock

RENAISSANCE TECHNOLOGIES LLC's Holding History (CIK: 0001037389)

Note: Option positions (PUT/CALL) are excluded.

Q3 2025

Shares 170,100 Value ($000) $2,380 Avg Close $11.40 Range $9.10 - $14.02

Q2 2025

Shares 135,100 Value ($000) $1,293 Avg Close $9.50 Range $6.42 - $12.00

Q1 2025

Shares 51,400 Value ($000) $478 Avg Close $12.94 Range $9.04 - $17.27

Q4 2024

Shares 29,100 Value ($000) $404 Avg Close $18.15 Range $13.27 - $29.60

Q1 2024

Shares 54,400 Value ($000) $1 Avg Close $16.40 Range $11.24 - $20.67

Q1 2022

Shares 29,300 Value ($000) $314 Avg Close $11.87 Range $9.74 - $14.27

Q4 2021

Shares 91,000 Value ($000) $1,280 Avg Close $19.87 Range $11.37 - $31.36

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2025	170,100	$2,380	$11.40	$9.10 - $14.02
Q2 2025	135,100	$1,293	$9.50	$6.42 - $12.00
Q1 2025	51,400	$478	$12.94	$9.04 - $17.27
Q4 2024	29,100	$404	$18.15	$13.27 - $29.60
Q1 2024	54,400	$1	$16.40	$11.24 - $20.67
Q1 2022	29,300	$314	$11.87	$9.74 - $14.27
Q4 2021	91,000	$1,280	$19.87	$11.37 - $31.36