ULTRAGENYX PHARMACEUTICAL IN

Ticker: RARE CUSIP: 90400D108 Class: EQTY

Frazier Life Sciences Management, L.P.'s Holding History (CIK: 0001892134)

Note: Option positions (PUT/CALL) are excluded.

Q3 2025

Shares 983,715 Value ($000) $29,590 Avg Close $29.99 Range $25.81 - $42.37

Q2 2025

Shares 983,715 Value ($000) $35,768 Avg Close $36.05 Range $29.59 - $40.19

Q1 2025

Shares 658,715 Value ($000) $23,852 Avg Close $41.60 Range $35.53 - $46.50

Q4 2024

Shares 658,715 Value ($000) $27,712 Avg Close $49.61 Range $41.26 - $57.99

Q3 2024

Shares 633,715 Value ($000) $35,203 Avg Close $50.94 Range $39.65 - $60.37

Q2 2024

Shares 425,000 Value ($000) $17,468 Avg Close $42.70 Range $37.02 - $52.56

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2025	983,715	$29,590	$29.99	$25.81 - $42.37
Q2 2025	983,715	$35,768	$36.05	$29.59 - $40.19
Q1 2025	658,715	$23,852	$41.60	$35.53 - $46.50
Q4 2024	658,715	$27,712	$49.61	$41.26 - $57.99
Q3 2024	633,715	$35,203	$50.94	$39.65 - $60.37
Q2 2024	425,000	$17,468	$42.70	$37.02 - $52.56